2-CYANO-3-METHOXYPYRIDINE
- Product Name
- 2-CYANO-3-METHOXYPYRIDINE
- CAS No.
- 24059-89-0
- Chemical Name
- 2-CYANO-3-METHOXYPYRIDINE
- Synonyms
- 3-METHOXYPICOLINONITRILE;2-CYANO-3-METHOXYPYRIDINE;3-Methoxy-2-Pyridinecarbonitrile;3-METHOXY-PYRIDINE-2-CARBONITRILE;2-Pyridinecarbonitrile, 3-methoxy-;2-CYANO-3-METHOXYPYRIDINE ISO 9001:2015 REACH
- CBNumber
- CB4760443
- Molecular Formula
- C7H6N2O
- Formula Weight
- 134.14
- MOL File
- 24059-89-0.mol
2-CYANO-3-METHOXYPYRIDINE Property
- Melting point:
- 111-112℃ (ethyl acetate )
- Boiling point:
- 289.8±20.0℃ (760 Torr)
- Density
- 1.16±0.1 g/cm3 (20 ºC 760 Torr)
- Flash point:
- 129.1±21.8℃
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- -4?+-.0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- M219115
- Product name
- 3-Methoxypyridine-2-carbonitrile
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 023712
- Product name
- 2-Cyano-3-methoxypyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
- Product number
- V4606
- Product name
- 3-methoxypyridine-2-carbonitrile
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 023712
- Product name
- 2-Cyano-3-methoxypyridine
- Purity
- 98%
- Packaging
- 5g
- Price
- $124
- Updated
- 2021/12/16
- Product number
- 023712
- Product name
- 2-Cyano-3-methoxypyridine
- Purity
- 98%
- Packaging
- 25g
- Price
- $377
- Updated
- 2021/12/16
2-CYANO-3-METHOXYPYRIDINE Chemical Properties,Usage,Production
Synthesis
124-41-4
38180-46-0
24059-89-0
Under nitrogen protection, sodium methanolate (0.41 g, 7.5 mmol) was dissolved in a 25 mL round bottom flask containing 10 mL of anhydrous N,N-dimethylformamide and the mixture was cooled to 4 °C using an ice water bath. Subsequently, 3-chloro-2-cyanopyridine (1.01 g, 7.2 mmol) was added to the reaction system, the ice-water bath was removed, and the reaction system was allowed to slowly warm up to 25 °C. After the reaction was carried out for 2 hours, the solvent was removed by vacuum concentration. Ethyl acetate was added to the concentrated residue and filtered to remove the insoluble precipitate. The filtrate was further concentrated on a rotary evaporator to afford the target product 2-cyano-3-methoxypyridine as a white solid (0.88 g, 88% yield), which could be used in subsequent reactions without further purification. The structure of the product was confirmed by 1H-NMR (CDCl3): δ 8.22 (dd, J = 7.4 and 1.6 Hz, 1H), 7.90 (dd, J = 7.5 and 7.3 Hz, 1H), 7.73 (dd, J = 7.73 and 1.6 Hz, 1H), 3.92 (s, 3H). Mass spectral analysis (ESI+) showed m/z (M + H)+ = 135.
References
[1] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 17, p. 5352 - 5359
[2] Patent: WO2015/187934, 2015, A1. Location in patent: Paragraph 0205
2-CYANO-3-METHOXYPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CYANO-3-METHOXYPYRIDINE manufacturers
- Product
- 2-CYANO-3-METHOXYPYRIDINE 24059-89-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-15