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TEMOCILLIN

Product Name: TEMOCILLIN
CAS No.: 61545-06-0
Chemical Name: TEMOCILLIN
Synonyms: emocillindisodium;BRL 17421 disodium;Temocillindisodiumsalt;(6S)-6-[(Sodiooxycarbonyl-3-thienylacetyl)amino]-6-methoxypenicillanic acid sodium salt;disodium [2S-(2α,5α,6α)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;(2S,5R,6S)-6-[[2-Carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt;4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)aMino)-6-Methoxy-3,3-diMethyl-7-oxo-, disodiuM salt, (2S,5R,6S)-;disodium [2S-(2alpha,5alpha,6alpha)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CBNumber: CB4761192
Molecular Formula: C16H18N2O7S2
Formula Weight: 414.45
MOL File: 61545-06-0.mol

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TEMOCILLIN Property

storage temp.: -20°C, stored under nitrogen
form: Solid
color: Off-white to yellow
Water Solubility: Water : 250 mg/mL (545.35 mM; Need ultrasonic)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T017320
Product name: TemocillinDisodium
Packaging: 1mg
Price: $160
Updated: 2021/12/16

Usbiological

Product number: 290644
Product name: Temocillin Disodium Salt
Packaging: 1mg
Price: $276
Updated: 2021/12/16

TRC

Product number: T017320
Product name: TemocillinDisodium
Packaging: 10mg
Price: $1260
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0026374
Product name: TEMOCILLIN DISODIUM SALT
Purity: 81.00%
Packaging: 5MG
Price: $829.63
Updated: 2021/12/16

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TEMOCILLIN Chemical Properties,Usage,Production

Uses

Temocillin Disodium is the salt of Temocillin, which is a β-lactam stable against most β-lactamases is used as an alternative to carbapenems.

Definition

ChEBI: Temocillin disodium is an organic sodium salt. It contains a temocillin(2-).

Biological Activity

Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell.

in vivo

Temocillin dosing regimens of 200 mg/kg every 4 and 6 h remained significantly effective in reducing bacterial titres in kidneys against the two strains, with no significant difference between the parental strain and its transconjugant^[2].

TEMOCILLIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from TEMOCILLIN manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: TEMOCILLIN 61545-06-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-09-04

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Temocillin Disodium Salt 61545-06-0
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 99% HPLC
Supply Ability: 10000
Release date: 2024-09-22

Hebei Yanxi Chemical Co., Ltd.

Product: TEMOCILLIN 61545-06-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-09

61545-06-0, TEMOCILLINRelated Search:

3-AZETIDINOL (2-ISOBUTYRYLAMINO-ACETYLAMINO)-ACETIC ACID 1-METHYL-3-AZETIDINOL TEMOCILLIN S-2-Hydroxyethyl-D-cysteine 3-METHOXY-AZETIDINE 3-Thiopheneacetic acid

disodium [2S-(2alpha,5alpha,6alpha)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

(6S)-6-[(Sodiooxycarbonyl-3-thienylacetyl)amino]-6-methoxypenicillanic acid sodium salt

Temocillindisodiumsalt

(2S,5R,6S)-6-[[2-Carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)aMino)-6-Methoxy-3,3-diMethyl-7-oxo-, disodiuM salt, (2S,5R,6S)-

BRL 17421 disodium

emocillindisodium

disodium [2S-(2α,5α,6α)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

61545-06-0

C16H16N2O7S22Na

C16H18N2O7S2