ChemicalBook > CAS DataBase List > UFP-101

UFP-101

Product Name
UFP-101
CAS No.
849024-68-6
Chemical Name
UFP-101
Synonyms
UFP-101;PubChem ID: 16152632;[NPHE1, ARG14, LYS15]NOCICEPTIN-NH2;N-(BZL)GLY-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN-NH2;N-(Bzl)Gly-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Arg-Lys-Asn-Gln-NH2 (N-(Bzl)GlyN-Benzylglycine);L-Glutamamide, N-(phenylmethyl)glycylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-arginyl-L-lysyl-L-asparaginyl- (9CI)
CBNumber
CB4763828
Molecular Formula
C82H138N32O21
Formula Weight
1908.17
MOL File
Mol file
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UFP-101 Property

storage temp. 
Desiccate at -20°C
form 
Powder
Water Solubility 
Soluble to 1 mg/ml in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1552
Product name
UFP-101
Packaging
1
Price
$364
Updated
2021/12/16
ApexBio Technology
Product number
B5128
Product name
UFP-101
Packaging
1mg
Price
$534
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000791
Product name
UFP-101
Purity
95.00%
Packaging
0.5MG
Price
$684.92
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000791
Product name
UFP-101
Purity
95.00%
Packaging
1MG
Price
$846.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000791
Product name
UFP-101
Purity
95.00%
Packaging
5MG
Price
$1829.52
Updated
2021/12/16
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UFP-101 Chemical Properties,Usage,Production

Uses

UFP-101 is a potent, selective, and competitive antagonist of the NOP receptor, with a pKi of 10.24. UFP-101 displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 shows antidepressant-like effect[1][2].

in vivo

UFP-101 elicits a pronounced acute and dosedependent antidepressant-like effect in mice submitted to the forced swimming test (FST)[1].

IC 50

NOP Receptor/ORL1

storage

Store at -20°C

References

[1] Calo G, et al. [Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor. Br J Pharmacol. 2002;136(2):303-311. DOI:10.1038/sj.bjp.0704706
[2] Gavioli EC, et al. Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test. Eur J Neurosci. 2003;17(9):1987-1990. DOI:10.1046/j.1460-9568.2003.02603.x

UFP-101 Preparation Products And Raw materials

Raw materials

Preparation Products

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UFP-101 Suppliers

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849024-68-6, UFP-101Related Search:


  • UFP-101
  • N-(BZL)GLY-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN-NH2
  • [NPHE1, ARG14, LYS15]NOCICEPTIN-NH2
  • N-(Bzl)Gly-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Arg-Lys-Asn-Gln-NH2 (N-(Bzl)GlyN-Benzylglycine)
  • PubChem ID: 16152632
  • L-Glutamamide, N-(phenylmethyl)glycylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-arginyl-L-lysyl-L-asparaginyl- (9CI)
  • 849024-68-6
  • C82H138N32O21
  • Opioid receptor and opioid-like receptor