UFP-101
- Product Name
- UFP-101
- CAS No.
- 849024-68-6
- Chemical Name
- UFP-101
- Synonyms
- UFP-101;PubChem ID: 16152632;[NPHE1, ARG14, LYS15]NOCICEPTIN-NH2;N-(BZL)GLY-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN-NH2;N-(Bzl)Gly-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Arg-Lys-Asn-Gln-NH2 (N-(Bzl)GlyN-Benzylglycine);L-Glutamamide, N-(phenylmethyl)glycylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-arginyl-L-lysyl-L-asparaginyl- (9CI)
- CBNumber
- CB4763828
- Molecular Formula
- C82H138N32O21
- Formula Weight
- 1908.17
- MOL File
- Mol file
UFP-101 Property
- storage temp.
- Desiccate at -20°C
- form
- Powder
- Water Solubility
- Soluble to 1 mg/ml in water
N-Bromosuccinimide Price
- Product number
- 1552
- Product name
- UFP-101
- Packaging
- 1
- Price
- $364
- Updated
- 2021/12/16
- Product number
- B5128
- Product name
- UFP-101
- Packaging
- 1mg
- Price
- $534
- Updated
- 2021/12/16
- Product number
- BRS0000791
- Product name
- UFP-101
- Purity
- 95.00%
- Packaging
- 0.5MG
- Price
- $684.92
- Updated
- 2021/12/16
- Product number
- BRS0000791
- Product name
- UFP-101
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $846.5
- Updated
- 2021/12/16
- Product number
- BRS0000791
- Product name
- UFP-101
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $1829.52
- Updated
- 2021/12/16
UFP-101 Chemical Properties,Usage,Production
Uses
UFP-101 is a potent, selective, and competitive antagonist of the NOP receptor, with a pKi of 10.24. UFP-101 displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 shows antidepressant-like effect[1][2].
in vivo
UFP-101 elicits a pronounced acute and dosedependent antidepressant-like effect in mice submitted to the forced swimming test (FST)[1].
IC 50
NOP Receptor/ORL1
storage
Store at -20°C
References
[1] Calo G, et al. [Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor. Br J Pharmacol. 2002;136(2):303-311. DOI:10.1038/sj.bjp.0704706
[2] Gavioli EC, et al. Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test. Eur J Neurosci. 2003;17(9):1987-1990. DOI:10.1046/j.1460-9568.2003.02603.x
UFP-101 Preparation Products And Raw materials
Raw materials
Preparation Products
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