1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE

Product Name: 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE
CAS No.: 4430-35-7
Chemical Name: 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE
Synonyms: 6-MITC;6-HITC;6-MITC; 6 MITC; 6MITC;6-METHYLSULFINYLHEXYL ISOTHIOCYANATE;1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE;Hexane, 1-isothiocyanato-6-(methylsulfinyl)-;6-(Methylsulfinyl)hexyl isothiocyanate (6-MITC), tumor cell proliferation inhibitor
CBNumber: CB4774237
Molecular Formula: C8H15NOS2
Formula Weight: 205.34
MOL File: Mol file

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1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE Property

Boiling point:: 385.9±25.0 °C(Predicted)
Density: 1.12±0.1 g/cm3(Predicted)
storage temp.: Refrigerator, under inert atmosphere
solubility: Chloroform (Sparingly), Methanol (Slightly)
form: Oil
color: Colourless to Pale Yellow
LogP: 0.959 (est)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3554
Product name: 6-(Methylsulfinyl)hexyl isothiocyanate
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $81.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML3554
Product name: 6-(Methylsulfinyl)hexyl isothiocyanate
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $327
Updated: 2024/03/01

Cayman Chemical

Product number: 19638
Product name: 6-Methylsulfinylhexyl Isothiocyanate
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 19638
Product name: 6-Methylsulfinylhexyl Isothiocyanate
Purity: ≥98%
Packaging: 5mg
Price: $122
Updated: 2024/03/01

Cayman Chemical

Product number: 19638
Product name: 6-Methylsulfinylhexyl Isothiocyanate
Purity: ≥98%
Packaging: 10mg
Price: $184
Updated: 2024/03/01

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1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE Chemical Properties,Usage,Production

Description

6-Methylsulfinylhexyl isothiocyanate (6-MSITC) is an isothiocyanate that has been found in wasabi (W. japonica) and has diverse biological activities. It inhibits nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at a concentration of 5 μM. It inhibits aggregation of isolated human platelets induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607; IC₅₀ = 21.9 μM). 6-MSITC reduces cell survival in a panel of breast, brain, colon, lung, ovarian, renal, and prostate cancer cell lines (mean IC₅₀ = 43.7 μM). In vivo, 6-MSITC (5 mg/kg twice weekly) reduces apoptosis of substantia nigral dopaminergic neurons and motor dysfunction in a mouse model of Parkinson''s disease induced by 6-OHDA . 6-MSITC also reduces the number of lung metastases in a B16/F10 murine melanoma model.

Uses

6-(Methylsulfinyl)hexyl isothiocyanate derived from Wasabia japonica was discovered as an inhibitor of glycogen synthase kinase-3β.

Definition

ChEBI: 1-isothiocyanato-6-(methylsulfinyl)hexane is a sulfoxide.

1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE Suppliers

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4430-35-7, 1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANERelated Search:

6-METHYLSULFINYLHEXYL ISOTHIOCYANATE

1-ISOTHIOCYANATO-6-(METHYLSULFINYL)-HEXANE

6-HITC

6-MITC

6-MITC; 6 MITC; 6MITC

Hexane, 1-isothiocyanato-6-(methylsulfinyl)-

6-(Methylsulfinyl)hexyl isothiocyanate (6-MITC), tumor cell proliferation inhibitor

4430-35-7

C8H15NOS2

Aliphatics, Sulfur & Selenium Compounds