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4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE

Product Name
4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE
CAS No.
37067-30-4
Chemical Name
4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE
Synonyms
4-MU-β-NAG;4-MU-GlcNAc;GLCNAC1-B-4MU;GLCNAC1-BETA-4MU;4-MU-BETA-D-GLCNAC;-2-((4-methyl-2-oxo-2H-chromen-7-yl);4-Methylumbelliferyl-N-acetyl-beta-D-;4-Methylumbelliferyl-2-acetamido-2-deoxy-;4-Methylumbelliferyl-β-N-acetylglucosamine;4-Methylumbelliferyl-β-N-acetylglucosaminide
CBNumber
CB4776943
Molecular Formula
C18H21NO8
Formula Weight
379.37
MOL File
37067-30-4.mol
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4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE Property

Melting point:
208-210 °C
Boiling point:
507.24°C (rough estimate)
Density 
1.4163 (rough estimate)
refractive index 
1.5740 (estimate)
storage temp. 
-20°C
solubility 
DMF: 20 mg/mL, clear, colorless
form 
Crystalline solid
pka
12.87±0.70(Predicted)
color 
White to Off-White
λmax
360nm(Phosphate buffer sol.)(lit.)
BRN 
1693397
Stability:
Light Sensitive - Protect from Light
LogP
0.340 (est)
CAS DataBase Reference
37067-30-4(CAS DataBase Reference)
EPA Substance Registry System
2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl]oxy]-4-methyl- (37067-30-4)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
10-21
HS Code 
29321900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
69585
Product name
4-Methylumbelliferyl N-acetyl-β-D-glucosaminide
Purity
suitable for fluorescence, ≥99.0% (TLC)
Packaging
1g
Price
$448
Updated
2024/03/01
Sigma-Aldrich
Product number
474502
Product name
4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide
Packaging
250mg
Price
$155
Updated
2024/03/01
TCI Chemical
Product number
M3030
Product name
4-Methylumbelliferyl 2-Acetamido-2-deoxy-β-D-glucopyranoside
Purity
>98.0%(HPLC)(N)
Packaging
250mg
Price
$160
Updated
2024/03/01
TCI Chemical
Product number
M3030
Product name
4-Methylumbelliferyl 2-Acetamido-2-deoxy-β-D-glucopyranoside
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$318
Updated
2024/03/01
Cayman Chemical
Product number
26953
Product name
4-Methylumbelliferyl 2-Acetamido-2-deoxy-β-D-glucopyranoside
Packaging
100mg
Price
$62
Updated
2024/03/01
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4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE Chemical Properties,Usage,Production

Chemical Properties

4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE is White Crystalline Solid

Uses

4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE is used for the assay of b-Acetylglucosaminidase. A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozy mes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis. They include Tay Sachs disease, Sandhoff disease and other forms. Fluorescence: max. Abs. l = 325nm, max. Em. l = 378nm

Uses

4-Methylumbelliferyl N-acetyl-β-D-glucosaminide has been used as a substrate for assaying

  • β-N-acetylglucosaminidase (NAGase) from soil samples
  • chitinase from Fusarium oxysporum using fluorimetric assay
  • β-N-acetylhexosaminidases from Arabidopsis thaliana roots and leaves samples

General Description

4-Methylumbelliferyl N-acetyl-β-D-glucosaminide (4-MUF-NAG) contains chitin monomer, N-acetyl-D-glucosamine (NAG) and a 4-methylumbelliferone (7-hydroxy-4-methylcoumarin) (4-MUF) moiety.

Biochem/physiol Actions

4-Methylumbelliferyl N-acetyl-β-D-glucosaminide (4-MUF-NAG) is a synthetic fluorogenic substrate for N-acetyl-β-D-glucosaminidase (NAGase). The enzyme functionality is assessed by its ability to hydrolyze the N-acetyl-D-glucosamine (NAG) residue in 4-MUF-NAG. 4-MUF-NAG is also a substrate for Chitinase and N-acetylhexosaminidase.

4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE Suppliers

Americas 1 Canada 1 China 138 Europe 1 France 2 Germany 4 India 5 Japan 3 Switzerland 4 United Kingdom 13 United States 17 USA 1 Global 190
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View Lastest Price from 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Methylumbelliferyl 2-Acetamido-2-deoxy-β-D-glucopyranoside 37067-30-4
Price
US $0.00/G
Min. Order
1G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-20
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE 37067-30-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE 37067-30-4
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-18

37067-30-4, 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDERelated Search:

Chloroacetone DEXTROSE FLUOROPENTACHLOROACETONE 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE 4-METHYLUMBELLIFERYL-N,N',N''-TRIACETYL-BETA-CHITOTRIOSIDE 4-Methylumbelliferyl2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside 4-Methylumbelliferyl3,4,6-tri-O-acetyl-2-deoxy-2-trifluoroacetamido-b-D-glucopyranoside 4-METHYLUMBELLIFERYL N-ACETYL-BETA-D-GLUCOSAMINIDE-6-SULFATE SODIUM SALT 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-b-D-glucopyranoside, Potassium Salt 4-METHYLUMBELLIFERYL BETA-D-N,N'-DIACETYL-CHITOBIOSIDE 4-METHYLUMBELLIFERYL BETA-D-N,N',N',N''-TETRAACETYLCHITOTETRAOSIDE 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3-O-(a-L-fucopyranosyl)-b-D-glucopyranoside 4-Methylumbelliferyl 2-Acetamido-2-deoxy-4-O-(a-L- fucopyranosyl)-b-D-glucopyranoside 4-METHYLUMBELLIFERYL LEWIS X TRISACCHARIDE 4-METHYLUMBELLIFERYL-N,N'-DIACETYL-BETA-D-CHITOBIOSIDE MONOHYDRATE 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE DIHYDRATE 250 MG 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE ANALYT. GR. 4-METHYLUMBELLIFERYL 4-DEOXY-B-D-CHITOBIOSE PERACETATE

  • 4-methylumberiferryl-N-acetyl-beta-D-glucosaminide.2H2O
  • 2-Oxo-4-methyl-2H-1-benzopyran-7-yl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside
  • 4-Methyl-2-oxo-2H-1-benzopyran-7-yl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside
  • 4-Methylumbelliferyl-β-N-acetylglucosamine
  • 4-Methylumbelliferyl-β-N-acetylglucosaminide
  • 4-MU-GlcNAc
  • 7-[[2-(Acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one
  • 4-Methylumbelliferyl-N-acetyl-beta-D-glucosaminide,99%
  • 4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-glucopyranoside ,98%
  • -METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE
  • 7-[[2-acetamido-2-deoxy-β-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one
  • 4-Methylumbellifery-2-acetamido-2-deoxy-β-D-glucopyranoside
  • 4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-SS-D-GLUCOPYRANOSIDE
  • 4-Methylumbelliferyl-N-acetyl-β-D-glucosaminide - CAS 37067-30-4 - Calbiochem
  • N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[(4-methyl-2-oxo-1-benzopyran-7-yl)oxy]-3-oxanyl]acetamide
  • 7-[[2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl]oxy]-2h-1-benzopyran-2-on
  • 4- MethyluMbelliferyl acetate -N- acetylaMino -BETA-D- glucose
  • 4-MU-β-NAG
  • 4-Methylumbelliferyl-2-acetamido-2-deoxy-
  • -2-((4-methyl-2-oxo-2H-chromen-7-yl)
  • 7-[[2-acetamido-2-deoxy-beta-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one
  • 4'-Methylumbelliferyl-2-acetamido-2-deoxy-b-D-glucopyranoside
  • 4-METHYLUMBELLIFERYL-N-ACETYL-B-D-*GLUCO SAMINIDE CR
  • 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLU COSAMINIDE DIHY.
  • 4-Methylumbelliferyl-N-acetyl-beta-D-
  • 4-Methylumbelliferyl-N-acetyl-D-glucosaminide GlcNAc1-b-4MU
  • Methylumbelliferyl-N-acetyl-b-D-glucosaminide
  • 4-methylumbelliferyl n-acetyl-β-d-glucosaminide dihydrate
  • GLCNAC1-BETA-4MU
  • GLCNAC1-B-4MU
  • 7-HYDROXY-4-METHYLCUMARIN-N-ACETYL-BETA-D-GLUCOSAMINID
  • 4-MU-BETA-D-GLCNAC
  • 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE
  • 4'-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE
  • 4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE
  • 4-METHYLUMBELLIFERYL-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSE
  • 4-Methylumbelliferyl-2-N-acetyl-D-glucosaminide
  • 2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-4-methyl-
  • 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-glucopyranoside
  • 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide
  • 4-METHYLUMBELLIFERYL-N-ACETYL-BETA-D-GLUCOSAMINIDE USP/EP/BP
  • 4-Methylumbelliferyl-N-Acetyl-β-D-Glucosaminide extrapure, 99%
  • 2H-1-Benzopyran-2-one,7-[[2-(acetylamino)-2-deoxy-b-D-glucopyranosyl]oxy]-4-methyl-
  • 4-MU 2-acetamido-2-deoxy-b-D-glucopyranoside
  • N-((2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-3-yl)acetamide
  • 4-Methylumbelliferyl N-acetyl-β-<sc>D</sc>-glucosaminide
  • 37067-30-4
  • C18H23NO8
  • BioChemical
  • Biochemicals and Reagents
  • Substrates by Enzyme
  • Enzyme Substrates
  • Fluorescent Probes, Labels, Particles and Stains
  • Acetylglucosaminidase, beta-N-
  • Detection
  • Enzymes, Inhibitors, and Substrates
  • Substrates
  • Sugars, Carbohydrates & Glucosides