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MURAMIC ACID

Product Name
MURAMIC ACID
CAS No.
1114-41-6
Chemical Name
MURAMIC ACID
Synonyms
MURAMIC ACID;MuramicAcid~99%;(+)-MURAMIC ACID;MURAMIC ACID, (+)-;aldehydo-muramicaci;aldehydo-muramic acid;MURAMIC ACID, (+)-(RG);MURAMIC ACID USP/EP/BP;MURAMIC ACID HYDRATE 98%;Muramic acid hydrate,98%
CBNumber
CB4783314
Molecular Formula
C9H17NO7
Formula Weight
251.23
MOL File
1114-41-6.mol
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MURAMIC ACID Property

Melting point:
140-150 °C (dec.)
alpha 
D25 +103° (c = 0.26 in water) (Matsushima, Park); D22 +146° (6 minutes) +116° (31 hrs) (c = 0.57 in water) (Osawa, Jeanloz)
Boiling point:
592.0±50.0 °C(Predicted)
Density 
1.448±0.06 g/cm3(Predicted)
Flash point:
14℃
storage temp. 
-20°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
pka
3.18±0.10(Predicted)
color 
White to Light Brown
optical activity
[α]25/D 95 to 120°, c =0.26% (w/v) in water
Water Solubility 
water: 20mg/mL, clear to very slightly hazy, colorless to faintly yellow
Merck 
13,6328
BRN 
1713780
Stability:
Hygroscopic
CAS DataBase Reference
1114-41-6(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
1
3-10
HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M2503
Product name
Muramic acid
Purity
≥95%
Packaging
5mg
Price
$130
Updated
2025/07/31
Sigma-Aldrich
Product number
M2503
Product name
Muramic acid
Purity
≥95%
Packaging
25mg
Price
$451
Updated
2025/07/31
Sigma-Aldrich
Product number
PH006652
Product name
Muramic acid
Purity
AldrichCPR
Packaging
5mg
Price
$367
Updated
2022/05/15
Usbiological
Product number
M5015
Product name
Muramic Acid
Packaging
5mg
Price
$446
Updated
2021/12/16
TRC
Product number
M800000
Product name
Muramic acid
Packaging
5mg
Price
$160
Updated
2021/12/16
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MURAMIC ACID Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Amino sugar found (as the N-acetyl derivative) in peptidoglycan, the main skeletal component of the bacterial cell wall. The N-acetyl derivative of muramic acid is an amino sugar that constitutes the peptidoglycan bacterial cell wall of Gram negative and Gram positive bacteria. Muramic acid is used as a chemical marker for the detection of bacterial contamination.

General Description

Muramic acid is a marker for Gram-positive bacteria.

Purification Methods

Muramic acid crystallises from H2O or aqueous EtOH as the monohydrate which loses H2O at 80o in vacuo over P2O5. It sometimes contains some NaCl. It has been purified by dissolving 3.2g in MeOH (75mL), filtering from some insoluble material, concentrating to ~10mL and refrigerating. The colourless crystals are washed with absolute MeOH. This process does not remove NaCl; to do so, the product is recrystallised from an equal weight of H2O to give a low recovery yield of very pure acid (0.12g). On paper chromatography 0.26_g give one ninhydrin positive spot after development with 75% phenol (RF 0.51) or with sec-BuOH/HCO2H/H2O (7:1:2) (RF 0.30). [Matsushima & Park Biochemical Preparations 10 109 1963, J Org Chem 27 3581 1962.] The acid has also been purified by dissolving 990mg in 50% aqueous EtOH (2mL), cooling, collecting the colourless needles on a sintered glass funnel and drying over P2O5 at 80o/0.1mm to give the anhydrous acid. [Lambert & Zilliken Chem Ber 93 2915 1960.] Alternatively the acid is dissolved in a small volume of H2O, neutralised to pH 7 with ion-exchange resin beads (IR4B in OH-form), filtered, evaporated and dried. The residue is recrystallised from 90% EtOH (v/v) and dried as above for 24hours. [Strange & Kent Biochem J 71 333 1959.] The N-acetyl derivative (NAMA, R-2-(acetylamino)-3-O -(1-carboxyethyl)-2-deoxy-D-glucose, R -2(2 -acetylamino-2-deoxy -D-glucose -3-yloxy)-propionic acid) [10597-89-4], M 292.3, has m ~125o (dec) and [] 20D +41.2o after 24hours (c 1.5, H2O), pKEst ~ 3.6. [Watanabe & Saito J Bacteriol 144 428 1980, Beilstein 4 IV 2029.]

MURAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from MURAMIC ACID manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Muramic acid 1114-41-6
Price
US $0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-09

1114-41-6, MURAMIC ACIDRelated Search:


  • 2-AMINO-3-O-[1-CARBOXYETHYL]-2-DEOXY-D-GLUCOSE
  • (R)-2-AMINO-3-O-(1-CARBOXYETHYL)-2-DEOXY-D-GLUCOSE
  • (+)-MURAMIC ACID
  • MURAMIC ACID
  • MURAMIC ACID, (+)-
  • MURAMIC ACID HYDRATE 98%
  • MuramicAcid~99%
  • 2-amino-3-o-(1-carboxyethyl)-2
  • 2-[3-amino-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoic acid
  • 2-Amino-3-O-[(R)-1-carboxyethyl]-2-deoxy-D-glucose
  • Muramic acid hydrate,98%
  • MURAMIC ACID, (+)-(RG)
  • ethyl 3-aMino-2-(o-tolyl)propanoate oxalate
  • aldehydo-muramic acid
  • (R)-N-Acetyl-4-O-[2-(acetylamino)-2-deoxy-&beta
  • -D-glucopyranosyl]-1,6-bis-O-(phenylmethyl)-&alpha
  • (2R)-2-[[(2S,3R,4R,5S,6R)-3-ammonio-2,5-dihydroxy-6-(hydroxymethyl)-4-oxanyl]oxy]propanoate
  • aldehydo-muramicaci
  • MURAMIC ACID USP/EP/BP
  • Muramic acid,2-Amino-3-O-(1-carboxyethyl) -2-deoxy-D-glucose
  • (R)-2-(((2R,3R,4R,5R)-2-Amino-4,5,6-trihydroxy-1-oxohexan-3-yl)oxy)propanoic acid
  • 1114-41-6
  • C9H17NO7H2O
  • C9H17NO7xH2O
  • C9H17NO7
  • Monosaccharide
  • BioChemical
  • Biochemicals and Reagents
  • Carbohydrates
  • 13C & 2H Sugars
  • aldehydes
  • Carbohydrates & Derivatives
  • Labeling and Diagnostics Reagents