ChemicalBook > CAS DataBase List > PROTAC Linker 27
PROTAC Linker 27
- Product Name
- PROTAC Linker 27
- CAS No.
- 1246286-33-8
- Chemical Name
- PROTAC Linker 27
- Synonyms
- Tos-PEG2-NH2;PROTAC Linker 27;2-(2-aminoethoxy)ethyl 4-methylbenzenesulfonate;Ethanol, 2-(2-aminoethoxy)-, 1-(4-methylbenzenesulfonate)
- CBNumber
- CB48054814
- Molecular Formula
- C11H17NO4S
- Formula Weight
- 259.32
- MOL File
- 1246286-33-8.mol
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PROTAC Linker 27 Property
- Boiling point:
- 414.5±30.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- pka
- 8?+-.0.10(Predicted)
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PROTAC Linker 27 Chemical Properties,Usage,Production
Biological Activity
Tos-PEG2-NH2 (PROTAC Linker 27) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
PROTAC Linker 27 Preparation Products And Raw materials
Raw materials
Preparation Products
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