ChemicalBook > CAS DataBase List > 1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide

1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide

Product Name
1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide
CAS No.
439088-16-1
Chemical Name
1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide
Synonyms
Elobixibat Impurity;Elobixibat Impurity 2;3,3-dibutyl-8-hydroxy-7-methylthio-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine dioxide;1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide;2,2-dibutyl-7-hydroxy-6-(methylthio)-4-phenyl-3,4-dihydro-2H-benzo[b][1,4]thiazine 1,1-dioxide;3,3-Dibutyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepine-1,1-dioxide;3,3-Dibutyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine 1,1-dioxide;Elobixibat Phenol ImpurityQ: What is Elobixibat Phenol Impurity Q: What is the CAS Number of Elobixibat Phenol Impurity
CBNumber
CB48084217
Molecular Formula
C24H33NO3S2
Formula Weight
447.65
MOL File
439088-16-1.mol
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1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide Property

Boiling point:
622.7±55.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
pka
7.78±0.40(Predicted)
InChI
InChI=1S/C24H33NO3S2/c1-4-6-13-24(14-7-5-2)17-25(19-11-9-8-10-12-19)20-15-22(29-3)21(26)16-23(20)30(27,28)18-24/h8-12,15-16,26H,4-7,13-14,17-18H2,1-3H3
InChIKey
HXBVVCHHTCHIGN-UHFFFAOYSA-N
SMILES
S1(=O)(=O)C2=CC(O)=C(SC)C=C2N(C2=CC=CC=C2)CC(CCCC)(CCCC)C1
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Hazard and Precautionary Statements (GHS)

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1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide Chemical Properties,Usage,Production

Uses

3,3-Dibutyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepine-1,1-dioxide is an intermediate of Elobixibat (E505200) which is an ileal sodium-dependent bile acid transporter ( IBAT) inhibitor, used for the treatment of chronic constipation and irritable bowel syndrome with constipation (IBS-C).

1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide Preparation Products And Raw materials

Raw materials

Preparation Products

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1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide Suppliers

Chengdu D-innovation Pharmaceutical Co.,LTD
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028-85929779 18881048017
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chenxuanruo@d-innovation.com
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China
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267
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Daicel Chiral Technologies (China)CO.,LTD
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021-50460086-9 15921403865
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+86-21-50462321
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Tianjin Kailiqi Biotechnology Co., Ltd.
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15076683720
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022-23754520
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NANJING ZENJI PHARMACEUTICALS
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0512-62750571
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028-87689268 18113025300
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JinOu Biomedical (Nanjing) Co., Ltd.
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Hubei Henghua Technology Co., Ltd.
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18064208139
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NANJING ZENJI PHARMACEUTICALS
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View Lastest Price from 1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
3,3-Dibutyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepine-1,1-dioxide 439088-16-1
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99.0%min
Supply Ability
200kg
Release date
2024-12-04

439088-16-1, 1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxideRelated Search:


  • 1,5-Benzothiazepin-8-ol, 3,3-dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-5-phenyl-, 1,1-dioxide
  • 3,3-dibutyl-8-hydroxy-7-methylthio-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine dioxide
  • Elobixibat Phenol ImpurityQ: What is Elobixibat Phenol Impurity Q: What is the CAS Number of Elobixibat Phenol Impurity
  • 3,3-Dibutyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepine 1,1-dioxide
  • 2,2-dibutyl-7-hydroxy-6-(methylthio)-4-phenyl-3,4-dihydro-2H-benzo[b][1,4]thiazine 1,1-dioxide
  • Elobixibat Impurity 2
  • 3,3-Dibutyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepine-1,1-dioxide
  • Elobixibat Impurity
  • 439088-16-1
  • C24H33NO3S2