Bempedoic Acid-d4
- Product Name
- Bempedoic Acid-d4
- CAS No.
- 2408131-70-2
- Chemical Name
- Bempedoic Acid-d4
- Synonyms
- Bempedoic Acid-d4;D4-Bempedoic Acid;8-Hydroxy-2,2,14,14-tetramethylpentadecanedioic-7,7,9,9-d4 acid;8-hydroxy-2,2,14,14-tetramethyl(7,7,9,9-2H?)pentadecanedioic acid;Bempedoic acid-D4Q: What is Bempedoic acid-D4 Q: What is the CAS Number of Bempedoic acid-D4
- CBNumber
- CB48175937
- Molecular Formula
- C19H36O5
- Formula Weight
- 344.49
- MOL File
- 2408131-70-2.mol
Bempedoic Acid-d4 Property
- form
- Solid
- color
- White to off-white
Bempedoic Acid-d4 Chemical Properties,Usage,Production
Uses
Bempedoic acid-d4 is the deuterium labeled Bempedoic acid. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor. Bempedoic acid (ETC-1002) activates AMPK[1][2].
References
[1] Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54(1):134-51. DOI:10.1194/jlr.M030528
[2] Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54(8):2095-108. DOI:10.1194/jlr.M035212
[3] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
Bempedoic Acid-d4 Preparation Products And Raw materials
Raw materials
Preparation Products
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