2H-1-Benzopyran-2-one, 7-(1,1-dimethyloctyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]-
- Product Name
- 2H-1-Benzopyran-2-one, 7-(1,1-dimethyloctyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]-
- CAS No.
- 1399049-81-0
- Chemical Name
- 2H-1-Benzopyran-2-one, 7-(1,1-dimethyloctyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]-
- Synonyms
- PSB-SB-487;PSB-SB-487, 10 mM in DMSO;5-hydroxy-3-(2-hydroxybenzyl)-7-(2-methylnonan-2-yl)-2H-chromen-2-one;5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)-2H-chromen-2-one;2H-1-Benzopyran-2-one, 7-(1,1-dimethyloctyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]-;GPR55,PSB SB 487,Inhibitor,G protein-coupled receptor 55,PSBSB487,Parkinson disease,cancer,neuropathic pain,diabetes,inhibit
- CBNumber
- CB48231406
- Molecular Formula
- C26H32O4
- Formula Weight
- 408.53
- MOL File
- 1399049-81-0.mol
2H-1-Benzopyran-2-one, 7-(1,1-dimethyloctyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]- Property
- Boiling point:
- 580.4±50.0 °C(Predicted)
- Density
- 1.147±0.06 g/cm3(Predicted)
- pka
- 7.53±0.20(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
2H-1-Benzopyran-2-one, 7-(1,1-dimethyloctyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]- Chemical Properties,Usage,Production
Uses
PSB-SB-487 is a potent GPR55 antagonist and CB2 agonist with an IC50 value of 0.113 μM for GPR55, and a Ki value of 0.292 μM for human CB2. PSB-SB-487 can be used for researching diabetes, Parkinson’s disease, neuropathic pain, and cancer[1].
References
[1] Viktor Rempel, et al. Antagonists for the orphan G-protein-coupled receptor GPR55 based on a coumarin scaffold. J Med Chem. 2013 Jun 13;56(11):4798-810. DOI:10.1021/jm4005175
2H-1-Benzopyran-2-one, 7-(1,1-dimethyloctyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
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