1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-
- Product Name
- 1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-
- CAS No.
- 1185329-96-7
- Chemical Name
- 1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-
- Synonyms
- IXA4;IXA4, 10 mM in DMSO;N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide;N-[1-({methyl[2-(4-methylphenoxy)ethyl]carbamoy l}methyl)-1H-pyrazol-4-yl]-3-phenoxypropanamide;1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-;endoplasmic reticulum (ER) proteostasis,UPR,protein secretion,Inhibitor,Inositol requiring enzyme 1,IXA4,IXA-4,IRE1,unfolded protein response,IXA 4,inhibit
- CBNumber
- CB48318488
- Molecular Formula
- C24H28N4O4
- Formula Weight
- 436.5
- MOL File
- 1185329-96-7.mol
1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]- Property
- Boiling point:
- 695.2±55.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 100 mg/mL (229.10 mM; Need ultrasonic)
- form
- A solid
- pka
- 13.84±0.70(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 027686
- Product name
- IXA4
- Packaging
- 001
- Price
- $300
- Updated
- 2021/12/16
1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]- Chemical Properties,Usage,Production
Biological Activity
IXA4 is a nontoxic, potent and highly selective IRE1-XBP1s signaling activator th at induce ER proteostasis remodeling. IXA4 reduced Aβ levels and prevents APP-associated mitochondrial dysfunction in CHO7PA2 cells expressing the V717F APP (APPV717F) mutant.
1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]- Preparation Products And Raw materials
Raw materials
Preparation Products
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