ChemicalBook > CAS DataBase List > 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE
1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE
- Product Name
- 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE
- CAS No.
- 547756-93-4
- Chemical Name
- 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE
- Synonyms
- JTE 013;1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea;1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE;N-(2,6-Dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide
- CBNumber
- CB4838782
- Molecular Formula
- C17H19Cl2N7O
- Formula Weight
- 408.28506
- MOL File
- 547756-93-4.mol
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1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Property
- storage temp.
- Store at +4°C
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N-Bromosuccinimide Price
Tocris
- Product number
- 2392
- Product name
- JTE013
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $233
- Updated
- 2021/12/16
TRC
- Product number
- J211998
- Product name
- JTE013
- Packaging
- 2.5mg
- Price
- $275
- Updated
- 2021/12/16
Usbiological
- Product number
- 255568
- Product name
- JTE 013
- Packaging
- 10mg
- Price
- $489
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0001569
- Product name
- 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE
- Purity
- 99.00%
- Packaging
- 50MG
- Price
- $1388.31
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0001569
- Product name
- 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE
- Purity
- 99.00%
- Packaging
- 10MG
- Price
- $253.05
- Updated
- 2021/12/16
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1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Chemical Properties,Usage,Production
Uses
JTE 013 is an antagonist of Sphingosine-1-Phosphate Receptor-2 (S1P2R).
Biological Activity
Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P 2 (EDG-5). Inhibits S1P binding to human S1P 2 receptors with an IC 50 value of 17.6 nM. At concentrations up to 10 μ M, displays 4.2% inhibition of S1P 3 and does not antagonize S1P 1 . Enhances S1P-induced angiogenesis in vivo .
1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE Suppliers
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547756-93-4, 1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDERelated Search:
Semicarbazide
1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE
6-HYDRAZINO-1,3,4-TRIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE