TERT-BUTYL 4-CYANOBENZYLCARBAMATE

Product Name: TERT-BUTYL 4-CYANOBENZYLCARBAMATE
CAS No.: 66389-80-8
Chemical Name: TERT-BUTYL 4-CYANOBENZYLCARBAMATE
Synonyms: N-Boc-4-cyanobenzylamine;4-BOC-AMINOMETHYL-BENZONITRILE;TERT-BUTYL 4-CYANOBENZYLCARBAMATE;tert-butyl N-[(4-cyanophenyl)methyl]carbamate;Carbamic acid, N-[(4-cyanophenyl)methyl]-, 1,1-dimethylethyl ester
CBNumber: CB4841968
Molecular Formula: C13H16N2O2
Formula Weight: 232.28
MOL File: 66389-80-8.mol

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TERT-BUTYL 4-CYANOBENZYLCARBAMATE Property

Melting point:: 90-92 °C
Boiling point:: 392.9±35.0 °C(Predicted)
Density: 1.10±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 11.91±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB140510
Product name: tert-Butyl 4-cyanobenzylcarbamate
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: 7357AJ
Product name: tert-Butyl4-cyanobenzylcarbamate
Packaging: 1g
Price: $151
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140510
Product name: tert-Butyl 4-cyanobenzylcarbamate
Packaging: 5G
Price: $260
Updated: 2021/12/16

Activate Scientific

Product number: AS29620
Product name: 4-(Boc-aminomethyl)benzonitrile
Purity: 95+%
Packaging: 5G
Price: $354
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140510
Product name: tert-Butyl 4-cyanobenzylcarbamate
Packaging: 10g
Price: $452.5
Updated: 2021/12/16

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TERT-BUTYL 4-CYANOBENZYLCARBAMATE Chemical Properties,Usage,Production

Synthesis

24424-99-5

15996-76-6

66389-80-8

(1) To a solution of 4-(aminomethyl)benzonitrile hydrochloride (5.00 g, 29.7 mmol) in dichloromethane (167 mL) at 0 °C was added sodium carbonate (7.54 g, 71.2 mmol). Subsequently, di-tert-butyl dicarbonate (7.57 mL, 32.6 mmol) was slowly added. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, water was added to terminate the reaction and the product was extracted with ethyl acetate. The organic layer was washed sequentially with water and saturated sodium chloride solution and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure, and the resulting crude product was purified by silica gel (NH) column chromatography (eluent: n-hexane/ethyl acetate=1:1) to give tert-butyl 4-cyanobenzylcarbamate (6.48 g, 94% yield).

References

[1] Angewandte Chemie - International Edition, 2012, vol. 51, # 18, p. 4431 - 4434
[2] Chemistry - A European Journal, 2018, vol. 24, # 68, p. 18075 - 18081
[3] Patent: WO2017/18803, 2017, A1. Location in patent: Paragraph 1552; 1553; 1554
[4] Journal of the American Chemical Society, 2012, vol. 134, # 25, p. 10317 - 10320
[5] Angewandte Chemie - International Edition, 2016, vol. 55, # 2, p. 528 - 533

TERT-BUTYL 4-CYANOBENZYLCARBAMATE Preparation Products And Raw materials

Raw materials

Preparation Products

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TERT-BUTYL 4-CYANOBENZYLCARBAMATE Suppliers

China 66 India 1 United Kingdom 1 United States 3 Global 71

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View Lastest Price from TERT-BUTYL 4-CYANOBENZYLCARBAMATE manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd

Product: TERT-BUTYL 4-CYANOBENZYLCARBAMATE 66389-80-8
Price: US $60.00-360.00/g
Min. Order: 5g
Purity: 99%
Supply Ability: 50
Release date: 2024-07-10

Zibo Hangyu Biotechnology Development Co., Ltd

Product: TERT-BUTYL 4-CYANOBENZYLCARBAMATE 66389-80-8
Price: US $55.00-700.00/g
Min. Order: 5g
Purity: 99%
Supply Ability: 50
Release date: 2024-07-12

Career Henan Chemical Co

Product: TERT-BUTYL 4-CYANOBENZYLCARBAMATE 66389-80-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2018-08-06

66389-80-8, TERT-BUTYL 4-CYANOBENZYLCARBAMATERelated Search:

TERT-BUTOXYCARBONYLAMINO-(4-CYANO-PHENYL)-ACETIC ACID N-BOC-3-(4-CYANOPHENYL)OXAZIRIDINE TERT-BUTYL 4-CYANO-3-FLUOROBENZYLCARBAMATE TERT-BUTYL 4-CYANOBENZYLCARBAMATE 3-N-Boc-3-(4-cyanophenyl)propionic acid 4-(DI-T-BOC-AMINOMETHYL)-3-CHLOROBENZONITRILE TERT-BUTYL 5-CYANOISOINDOLINE-2-CARBOXYLATE TERT-BUTYL 2-CHLORO-4-CYANOBENZYLCARBAMATE (S)-BOC-4-CYANO-BETA-PHE-OH tert-butyl 6-cyano-3,4-dihydroisoquinoline-2(1H)-carboxylate (R)-BOC-4-CYANO-BETA-PHE-OH N,N-DI-BOC-4-AMINOMETHYL BENZONITRILE Benzeneacetic acid,4-nitro-, 1,1-dimethylethyl ester CARBAMIC ACID, (3-BROMO-2-PYRIDINYL)-, 1,1-DIMETHYLETHYL ESTER tert-butyl 6-broMonaphthalen-2-ylcarbaMate tert-Butyl 7-amino-1H-indole-1-carboxylate TERT-BUTYL 2-CYCLOHEXYLHYDRAZINECARBOXYLATE [1-(4-BROMO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

TERT-BUTYL 4-CYANOBENZYLCARBAMATE

4-BOC-AMINOMETHYL-BENZONITRILE

N-Boc-4-cyanobenzylamine

tert-butyl N-[(4-cyanophenyl)methyl]carbamate

Carbamic acid, N-[(4-cyanophenyl)methyl]-, 1,1-dimethylethyl ester

66389-80-8