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LOE 908 HYDROCHLORIDE

Product Name
LOE 908 HYDROCHLORIDE
CAS No.
149759-26-2
Chemical Name
LOE 908 HYDROCHLORIDE
Synonyms
LOE 908;Pinokalant;LOE 908 HYDROCHLORIDE;1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-;3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
CBNumber
CB4845678
Molecular Formula
C41H48N2O9
Formula Weight
712.83
MOL File
149759-26-2.mol
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LOE 908 HYDROCHLORIDE Property

Boiling point:
803.7±65.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
form 
Solid
pka
5.47±0.20(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2314
Product name
LOE908hydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$173
Updated
2021/12/16
Tocris
Product number
2314
Product name
LOE908hydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$720
Updated
2021/12/16
Usbiological
Product number
255698
Product name
LOE 908 hydrochloride
Packaging
10mg
Price
$423
Updated
2021/12/16
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LOE 908 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

LOE 908 Hydrochloride is a isoquinoline derivative and a cation channel blocker. LOE 908 Hydrochloride is a neuroprotective agent.

Biological Activity

Broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na + and K + channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.

in vivo

Pinokalant significantly reduces cortical infarct volume from 33.8 mm3 to 24.5 mm3[1].

LOE 908 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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LOE 908 HYDROCHLORIDE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Guangzhou Yansai Biological Products Co., Ltd.
Tel
13710209565
Country
CHINA
ProdList
122
Advantage
58
Guangzhou Tuoshan Biotechnology Co., Ltd.
Tel
19928332050
Country
CHINA
ProdList
161
Advantage
58

149759-26-2, LOE 908 HYDROCHLORIDERelated Search:


  • LOE 908 HYDROCHLORIDE
  • LOE 908
  • 3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
  • Pinokalant
  • 1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-
  • 149759-26-2
  • C41H48N2O9HCl