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LOE 908 HYDROCHLORIDE

Product Name
LOE 908 HYDROCHLORIDE
CAS No.
149759-26-2
Chemical Name
LOE 908 HYDROCHLORIDE
Synonyms
LOE 908;Pinokalant;LOE 908 HYDROCHLORIDE;1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-;3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
CBNumber
CB4845678
Molecular Formula
C41H48N2O9
Formula Weight
712.83
MOL File
149759-26-2.mol
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LOE 908 HYDROCHLORIDE Property

Boiling point:
803.7±65.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at RT
form 
Solid
pka
5.47±0.20(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2314
Product name
LOE908hydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$173
Updated
2021/12/16
Tocris
Product number
2314
Product name
LOE908hydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$720
Updated
2021/12/16
Usbiological
Product number
255698
Product name
LOE 908 hydrochloride
Packaging
10mg
Price
$423
Updated
2021/12/16
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LOE 908 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

LOE 908 Hydrochloride is a isoquinoline derivative and a cation channel blocker. LOE 908 Hydrochloride is a neuroprotective agent.

Biological Activity

Broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na + and K + channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.

in vivo

Pinokalant significantly reduces cortical infarct volume from 33.8 mm3 to 24.5 mm3[1].

LOE 908 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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LOE 908 HYDROCHLORIDE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32470
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24964
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Shanghai Amole Biotechnology Co., Ltd.
Tel
18916360931 18916360931
Email
2596183085@qq.com
Country
China
ProdList
17236
Advantage
58
Guangzhou Yansai Biological Products Co., Ltd.
Tel
13710209565
Country
CHINA
ProdList
122
Advantage
58

149759-26-2, LOE 908 HYDROCHLORIDERelated Search:


  • LOE 908 HYDROCHLORIDE
  • LOE 908
  • 3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
  • Pinokalant
  • 1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-
  • 149759-26-2
  • C41H48N2O9HCl