ChemicalBook > CAS DataBase List > LOE 908 HYDROCHLORIDE
LOE 908 HYDROCHLORIDE
- Product Name
- LOE 908 HYDROCHLORIDE
- CAS No.
- 149759-26-2
- Chemical Name
- LOE 908 HYDROCHLORIDE
- Synonyms
- LOE 908;Pinokalant;LOE 908 HYDROCHLORIDE;1-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-;3,4-Dihydro-6,7-dimethoxy-α-phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride
- CBNumber
- CB4845678
- Molecular Formula
- C41H48N2O9
- Formula Weight
- 712.83
- MOL File
- 149759-26-2.mol
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LOE 908 HYDROCHLORIDE Property
- Boiling point:
- 803.7±65.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- form
- Solid
- pka
- 5.47±0.20(Predicted)
- color
- Off-white to light yellow
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N-Bromosuccinimide Price
Tocris
- Product number
- 2314
- Product name
- LOE908hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $173
- Updated
- 2021/12/16
Tocris
- Product number
- 2314
- Product name
- LOE908hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $720
- Updated
- 2021/12/16
Usbiological
- Product number
- 255698
- Product name
- LOE 908 hydrochloride
- Packaging
- 10mg
- Price
- $423
- Updated
- 2021/12/16
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LOE 908 HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
LOE 908 Hydrochloride is a isoquinoline derivative and a cation channel blocker. LOE 908 Hydrochloride is a neuroprotective agent.
Biological Activity
Broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na + and K + channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.
in vivo
Pinokalant significantly reduces cortical infarct volume from 33.8 mm3 to 24.5 mm3[1].
LOE 908 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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LOE 908 HYDROCHLORIDE Suppliers
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