4-BROMO-3-PHENYL-1H-PYRAZOLE
- Product Name
- 4-BROMO-3-PHENYL-1H-PYRAZOLE
- CAS No.
- 13808-65-6
- Chemical Name
- 4-BROMO-3-PHENYL-1H-PYRAZOLE
- Synonyms
- 4-Bromo-3-phenylpyrazole;4-bromo-5-phenyl-1H-pyrazole;3-phenyl-4-bromo-1H-pyrazole;4-BROMO-3-PHENYL-1H-PYRAZOLE;1H-Pyrazole, 4-bromo-3-phenyl-;4-bromo-3(5)-phenyl-1H-pyrazole;4-Bromo-3-phenyl-1(2)H-pyrazole
- CBNumber
- CB4847647
- Molecular Formula
- C9H7BrN2
- Formula Weight
- 223.07
- MOL File
- 13808-65-6.mol
4-BROMO-3-PHENYL-1H-PYRAZOLE Property
- Melting point:
- 116-117 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 365.8±22.0 °C(Predicted)
- Density
- 1.565±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- 12.23±0.50(Predicted)
- color
- White to Light yellow
Safety
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B5181
- Product name
- 4-Bromo-3-phenylpyrazole
- Purity
- min. 98.0 %
- Packaging
- 200MG
- Price
- $50
- Updated
- 2025/07/31
- Product number
- B5181
- Product name
- 4-Bromo-3-phenylpyrazole
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $149
- Updated
- 2025/07/31
- Product number
- B698548
- Product name
- 4-Bromo-3-phenyl-1(2)H-pyrazole
- Packaging
- 500mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- V2795
- Product name
- 4-Bromo-3-phenyl-1(2)H-pyrazole
- Packaging
- 1g
- Price
- $186
- Updated
- 2021/12/16
- Product number
- 3H31-9-44
- Product name
- 4-Bromo-3-phenyl-1H-pyrazole
- Packaging
- 1g
- Price
- $285
- Updated
- 2021/12/16
4-BROMO-3-PHENYL-1H-PYRAZOLE Chemical Properties,Usage,Production
Synthesis
2458-26-6
13808-65-6
The general procedure for the synthesis of 4-bromo-3-phenyl-1H-pyrazole from 3-phenyl-1H-pyrazole was as follows: 3-phenyl-1H-pyrazole (4.08 g, 28.3 mmol) and N-bromosuccinimide (NBS, 5.04 g, 28.3 mmol) were dissolved in N,N-dimethylformamide (DMF, 40 mL), and the reaction was stirred for 1 h at room temperature. After completion of the reaction, the reaction mixture was poured into water and extracted with ethyl acetate (AcOEt). The organic phases were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate (MgSO?) and concentrated under reduced pressure to remove the solvent. The resulting residue was recrystallized by hexane/ethyl acetate mixed solvent to give the title compound 4-bromo-3-phenyl-1H-pyrazole (5.84 g, 93% yield) as a white solid with a melting point of 114-116 °C. The NMR hydrogen spectrum (300 MHz, CDCl?) data were as follows: δ 7.39-7.50 (m, 3H), 7.64 (s, 1H), 7.77 (d, J = 6.8 Hz, 2H), 10.73 (brs, 1H).
References
[1] Patent: US2010/197651, 2010, A1. Location in patent: Page/Page column 68
[2] Patent: WO2008/150827, 2008, A1. Location in patent: Page/Page column 57
[3] Inorganica Chimica Acta, 2010, vol. 363, # 7, p. 1332 - 1342
[4] Tetrahedron Letters, 2017, vol. 58, # 43, p. 4111 - 4114
[5] Chemische Berichte, 1895, vol. 28, p. 688
4-BROMO-3-PHENYL-1H-PYRAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
4-BROMO-3-PHENYL-1H-PYRAZOLE Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 4-BROMO-3-PHENYL-1H-PYRAZOLE manufacturers
- Product
- 4-BROMO-3-PHENYL-1H-PYRAZOLE 13808-65-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-30