Fendiline
- Product Name
- Fendiline
- CAS No.
- 13042-18-7
- Chemical Name
- Fendiline
- Synonyms
- N-(1-Phenylethyl)-3,3-diphenylpropylamine;3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;Benzenepropanamine, γ-phenyl-N-(1-phenylethyl)-
- CBNumber
- CB4874928
- Molecular Formula
- C23H25N
- Formula Weight
- 315.45
- MOL File
- 13042-18-7.mol
Fendiline Property
- Boiling point:
- bp0.3 206-210°
- Density
- 1.031±0.06 g/cm3(Predicted)
- pka
- 9.49±0.28(Predicted)
- Water Solubility
- 2.331mg/L(22.5 ºC)
N-Bromosuccinimide Price
- Product number
- API0008688
- Product name
- FENDILINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.96
- Updated
- 2021/12/16
Fendiline Chemical Properties,Usage,Production
Originator
Sensit,Thiemann,W. Germany,1974
Definition
ChEBI: 3,3-diphenyl-N-(1-phenylethyl)-1-propanamine is a diarylmethane.
Manufacturing Process
21.13 grams of γ,γ-diphenyl-propylamine and 12.01 grams of acetophenone
are hydrogenated in 200 ml of methanol at 55°C and a pressure of 10
atmospheres in the presence of palladium charcoal. On filtration of the
catalyst the solution is concentrated and the remainder is distilled in vacuo at
a pressure of 0.3 Hg mm. The main distillate is collected at 206° to 210°C.
25.38 grams of N-[1'-phenylethyl-(1')]-1,1-diphenyl-propyl-(3)-amine are
obtained.
The product is dissolved in 134 ml of 96% ethanol whereupon 26.8 ml of
concentrated hydrochloric acid and 201 ml of water are added while cooling
with ice-water. The precipitate is filtered off and dried in vacuo at 100°C.
22.98 grams of N-[1'-phenylethyl)-(1')]-1,1-diphenyl-propyl-(3)-amine
hydrochloride are obtained. MP 200° to 201°C. On recrystallization from 285
ml of a 2:1 mixture of water and 96% ethanol the melting point remains
unchanged.
Therapeutic Function
Coronary vasodilator
Fendiline Preparation Products And Raw materials
Raw materials
Preparation Products
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