pipazetate hydrochloride
- Product Name
- pipazetate hydrochloride
- CAS No.
- 6056-11-7
- Chemical Name
- pipazetate hydrochloride
- Synonyms
- Selgon;Selvjgon;Lenopect;Selvigon;Pipazetate HCl;Theratuss Hydrochloride;pipazetate hydrochloride;Pipazethate hydrochloride;FEUBUXUFKHXRKO-UHFFFAOYSA-N;Pipazethate Monohydrochloride
- CBNumber
- CB4875480
- Molecular Formula
- C21H25N3O3S.ClH
- Formula Weight
- 435.973
- MOL File
- 6056-11-7.mol
pipazetate hydrochloride Property
- Melting point:
- 160-161°
Safety
- Toxicity
- LD50 orally in rats: 560 mg/kg (Schuler)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- P475700
- Product name
- PipazetateHydrochloride
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 019745
- Product name
- Pipazetate Hydrochloride
- Packaging
- 10mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- API0016766
- Product name
- PIPAZETHATE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $329.7
- Updated
- 2021/12/16
- Product number
- 52790
- Product name
- PipazetateHCl
- Packaging
- 10mg
- Price
- $650
- Updated
- 2021/12/16
pipazetate hydrochloride Chemical Properties,Usage,Production
Originator
Theratuss, Squibb ,US ,1962
Uses
Pipazetate Hydrochloride, a pyridobenzothiazine derivative an antiarrhythmic characteristics. Pipazetate is used as a cough supressant.
Manufacturing Process
8.5 parts of 1-azaphenothiazine carboxylic acid chloride and 14 parts of piperidino-ethoxyethanol were introduced into 100 parts of chlorobenzene and the mixture boiled under reflux for 5 minutes. After cooling off the precipitated hydrochloride salt of piperidino-ethoxyethanol was filtered off on a suction filter. Water was added to the filtrate and the pH thereof adjusted to 5 to 6 with dilute HCl. The aqueous phase was then removed, a caustic soda solution added thereto and then extracted with ether. The ethyl extract was washed with water, then dried with potash and the ether distilled off. 9.4 parts of the piperidino-ethoxy-ethyl ester of 1-azaphenothiazine carboxylic acid were obtained. This product was dissolved in 20 parts of isopropanol and the solution neutralized with isopropanolic HCl. The monohydrochloride which precipitated out after recrystallization from isopropanol had a melting point of 160°C to 161°C.
Therapeutic Function
Antitussive
pipazetate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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