pipradrol hydrochloride
- Product Name
- pipradrol hydrochloride
- CAS No.
- 71-78-3
- Chemical Name
- pipradrol hydrochloride
- Synonyms
- Gerodyl;MRD 108;Pyridrol;Piridrol;Pipralon;Meratran;Pyridrole;a-Pipradol;Pipradol hydrochloride;Pyridrol hydrochloride
- CBNumber
- CB4875642
- Molecular Formula
- C18H21NO.ClH
- Formula Weight
- 303.831
- MOL File
- 71-78-3.mol
pipradrol hydrochloride Property
- Melting point:
- 298-300?C
- storage temp.
- Controlled Substance, -20°C Freezer
- solubility
- DMSO: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; Methanol: 1 mg/ml; PBS (pH 7.2): 0.5 mg/ml
- form
- A crystalline solid
N-Bromosuccinimide Price
- Product number
- 14783
- Product name
- Pipradrol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $79
- Updated
- 2023/06/20
- Product number
- 14783
- Product name
- Pipradrol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $140
- Updated
- 2023/06/20
- Product number
- 14783
- Product name
- Pipradrol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $523
- Updated
- 2023/06/20
- Product number
- 3848CA
- Product name
- Pipradrolhydrochloride
- Packaging
- 10mg
- Price
- $257
- Updated
- 2021/12/16
pipradrol hydrochloride Chemical Properties,Usage,Production
Description
Pipradrol is a mild stimulant containing a piperidine ring. Once used as a treatment for obesity and dementia, pipradrol is now regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.
Chemical Properties
White Solid
Originator
Alertonic ,Adcock Ingram Ltd.
Uses
Controlled substance (stimulant). CNS stimulant
Definition
ChEBI: Pipradrol hydrochloride is a diarylmethane.
Manufacturing Process
A mixture of 48 g (0.167 mole) of α,α-diphenyl-2-pyridinemethanol hydrochloride (Emraert et al., Ber. 72B, 1188 (1939); 74B, 714 (1940), 160 ml of ethanol, and 3 0.5 g of Adams' platinum catalyst was shaken under an initial hydrogen pressure of 60 pounds. The theoretical amount of hydrogen was absorbed in 5 hours. The reaction mixture was refluxed, diluted with enough water to dissolve all the white solid, and filtered hot from the catalyst. The filtrate was cooled and filtered; yield of 38 g of α,α-diphenyl-alpha-(2piperidyl)methanol white product melting at 308-309°C with decomposition.
A mixture of 3.5 grams (0.013 mole) of the above α,α-diphenyl-alpha-(2piperidyl)methanol, 4 g (0.05 mole) of formaldehyde (37%), and 6 grams (0.1 mole) of formic acid was refluxed for 2 days. The reaction mixture was treated with 1.3 g (0.013 mole) of conc. hydrochloric acid and vacuum distilled on the steam bath. The residue was recrystallized from butanone to give the α,αdiphenyl-alpha-(2-piperidyl)methanol hydrochloride which melted at 228229°C (dec.).
brand name
Meratran (Marion Merrell Dow).
Therapeutic Function
Central stimulant
Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.