5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester

Product Name
5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
CAS No.
1847464-89-4
Chemical Name
5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
Synonyms
Mobocertinib succinate intermediate;5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
CBNumber
CB49018527
Molecular Formula
C29H35N7O5
Formula Weight
561.64
MOL File
1847464-89-4.mol
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5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Property

Boiling point:
754.3±70.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
pka
9.00±0.28(Predicted)
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Hazard and Precautionary Statements (GHS)

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5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Chemical Properties,Usage,Production

Description

The IUPAC Name of 5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester is isopropyl 2-((4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxy-5-nitrophenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate. This compound is an intermediate of Mobocertinib succinate which is an orally active and irreversible EGFR/HER2 inhibitor.

5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Suppliers

China 1 Global 1
Enki Biopharmaceuticals (Shanghai) Limited
Tel
+86-0086-2157680326 +8613916707528
Email
yusu@enkibiopharma.com
Country
China
ProdList
46
Advantage
58

1847464-89-4, 5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl esterRelated Search:


  • 5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
  • Mobocertinib succinate intermediate
  • 1847464-89-4