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levallorphan

Product Name
levallorphan
CAS No.
152-02-3
Chemical Name
levallorphan
Synonyms
C07069;MCL 113;Naloxiphan;Levalorfano;levallorphan;Levallorphane;Levallorphanum;17-Allylmorphinan-3-ol;N-Allyl-3-hydroxymorphinan;l-N-Allyl-3-hydroxymorphinan
CBNumber
CB4928450
Molecular Formula
C19H25NO
Formula Weight
283.41
MOL File
152-02-3.mol
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levallorphan Property

Melting point:
180-182°
alpha 
D20 -88.9° (c = 3 in methanol)
Boiling point:
425.96°C (rough estimate)
Density 
1.0260 (rough estimate)
refractive index 
1.5000 (estimate)
pka
10.17±0.20(Predicted)
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Safety

Hazardous Substances Data
152-02-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0009181
Product name
LEVALLORPHAN
Purity
95.00%
Packaging
5MG
Price
$495.28
Updated
2021/12/16
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levallorphan Chemical Properties,Usage,Production

Definition

ChEBI: Levallorphan is a morphinane alkaloid.

brand name

Lorfan (Roche).

Clinical Use

Levallorphan is an opioid antagonist with practically no analgesic action. It has been used as one of the first relative pure antagonists for the treatment of opioid overdosage, to reverse opioid central depression and to antagonize opioidinduced respiratory impairment . The compound is now replaced by naloxone .

Synthesis

Starting material for the levallorphan synthesis is 1-(4-methoxybenzyl)- 1,2,3,4,5,6,7,8-octahydro isoquinoline (1) .

Purification Methods

It crystallises from aqueous EtOH. It is a narcotic antagonist. [Schneider & Grüssner Helv Chim Acta 34 2211 1951, Hellerbach Helv Chim Acta 39 429 1956.]

levallorphan Preparation Products And Raw materials

Raw materials

Preparation Products

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levallorphan Suppliers

Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Jinan Ruisi Pharmaceutical Technology Co., LTD
Tel
0531-69900633 18340090523
Email
changyuan20@163.com
Country
China
ProdList
2687
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19699
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 13308200041
Email
2851167782@qq.com
Country
China
ProdList
11183
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19881
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Shaanxi Didu New Materials Co. Ltd
Tel
+86-89586680 +86-13289823923
Email
1026@dideu.com
Country
China
ProdList
8670
Advantage
58

152-02-3, levallorphanRelated Search:


  • 17-(2-propenyl)morphinan-3-ol
  • C07069
  • levallorphan
  • (-)-3-Hydroxy-N-allylmorphinan
  • 17-Allylmorphinan-3-ol
  • 2H-10,4a-Iminoethanophenanthren-6-ol, 11-allyl-1,3,4,9,10,10a-hexahydro- (6CI)
  • l-N-Allyl-3-hydroxymorphinan
  • MCL 113
  • Morphinan-3-ol, 17-(2-propenyl)- (9CI)
  • Morphinan-3-ol, 17-allyl- (8CI)
  • N-Allyl-3-hydroxymorphinan
  • Morphinan-3-ol, 17-(2-propen-1-yl)-
  • Levallorphane
  • Levallorphanum
  • Levalorfano
  • Naloxiphan
  • 152-02-3