2,6-Difluoro-4-nitrophenol
- Product Name
- 2,6-Difluoro-4-nitrophenol
- CAS No.
- 658-07-1
- Chemical Name
- 2,6-Difluoro-4-nitrophenol
- Synonyms
- 4-nitro-2,6-Difluorophenol;2,6-Difluoro-4-nitrophenol;Phenol, 2,6-difluoro-4-nitro-;2,6-Difluoro-4-nitrophenol 98%;2,6-Difluoro-4-nitrophenol，GC，97%;3,5-Difluoro-4-hydroxynitrobenzene
- CBNumber
- CB4969909
- Molecular Formula
- C6H3F2NO3
- Formula Weight
- 175.09
- MOL File
- 658-07-1.mol
2,6-Difluoro-4-nitrophenol Property
- Melting point:
- 99.7-100.7°C
- Boiling point:
- 254.5±40.0 °C(Predicted)
- Density
- 1.619±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- crystalline powder
- pka
- 4.28±0.44(Predicted)
- color
- Faint yellow
- InChI
- InChI=1S/C6H3F2NO3/c7-4-1-3(9(11)12)2-5(8)6(4)10/h1-2,10H
- InChIKey
- KVVXRISUSPIMLJ-UHFFFAOYSA-N
- SMILES
- C1(O)=C(F)C=C([N+]([O-])=O)C=C1F
Safety
- Hazard Codes
- Xi
- HS Code
- 2908990000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- D447213
- Product name
- 2,6-Difluoro-4-nitrophenol
- Packaging
- 500mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- W7705
- Product name
- 2,6-Difluoro-4-nitrophenol
- Packaging
- 1g
- Price
- $159
- Updated
- 2021/12/16
- Product number
- PC9845
- Product name
- 2,6-Difluoro-4-nitrophenol
- Purity
- 98%
- Packaging
- 5g
- Price
- $164
- Updated
- 2021/12/16
- Product number
- CS-W006721
- Product name
- 2,6-Difluoro-4-nitrophenol
- Purity
- 99.96%
- Packaging
- 5g
- Price
- $226
- Updated
- 2021/12/16
- Product number
- PC9845
- Product name
- 2,6-Difluoro-4-nitrophenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
2,6-Difluoro-4-nitrophenol Chemical Properties,Usage,Production
Chemical Properties
Light yellow crystalline
Synthesis
28177-48-2
141-78-6
658-07-1
The general procedure for the synthesis of 2,6-difluoro-4-nitrophenol from 2,6-difluorophenol and ethyl acetate is as follows: with reference to Example 103, 2,6-difluorophenol (2.00 g) was dissolved in acetic acid (20 ml), and 60% nitric acid (1.20 ml) was slowly added dropwise under ice bath conditions. After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, the mixture was poured into ice water and extracted with ethyl acetate. The extract was washed with saturated saline and the organic layer was dried with anhydrous magnesium sulfate. The dried organic layer was filtered and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography with the eluent being a mixed solvent with the volume ratio of hexane/ethyl acetate=3/1→2/1, resulting in the target compound 2,6-difluoro-4-nitrophenol (1.37 g, 51% yield) as a light yellow solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3), δppm: 7.95 (2H, m).
References
[1] Patent: US6555556, 2003, B1
2,6-Difluoro-4-nitrophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-Difluoro-4-nitrophenol manufacturers
- Product
- 2,6-Difluoro-4-nitrophenol 658-07-1
- Price
- US $22.00-88.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50kg
- Release date
- 2025-06-25
- Product
- 2,6-Difluoro-4-nitrophenol 658-07-1
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%MIN
- Supply Ability
- ASK
- Release date
- 2019-12-25