ChemicalBook > CAS DataBase List > BOC-12-ADO-OH

BOC-12-ADO-OH

Product Name
BOC-12-ADO-OH
CAS No.
18934-81-1
Chemical Name
BOC-12-ADO-OH
Synonyms
BOC-12-ADO-OH;BOC-NH-(CH2)11-COOH;BOC-12-AMINOLAURIC ACID;12-Boc-aminododecanic acid;Boc-12-Ado-OH >=98.0% (TLC);BOC-12-AMINODODECANOIC ACID;12-(BOC-AMINO)DODECANOIC ACID;N-Boc-12-aminododecanoic acid;T-BUTOXYCARBONYL-12-AMINOLAURIC ACID;T-BUTOXYCARBONYL-12-AMINODODECANOIC ACID
CBNumber
CB5104471
Molecular Formula
C17H33NO4
Formula Weight
315.45
MOL File
18934-81-1.mol
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BOC-12-ADO-OH Property

Melting point:
83.5-84.5 °C
Boiling point:
454.5±18.0 °C(Predicted)
Density 
0.997±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
pka
4.78±0.10(Predicted)
form 
powder
color 
colorless to white
BRN 
1980302
InChI
InChI=1S/C17H33NO4/c1-17(2,3)22-16(21)18-14-12-10-8-6-4-5-7-9-11-13-15(19)20/h4-14H2,1-3H3,(H,18,21)(H,19,20)
InChIKey
NNPOZNVKUHYVEJ-UHFFFAOYSA-N
SMILES
C(O)(=O)CCCCCCCCCCCNC(OC(C)(C)C)=O
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
09780
Product name
Boc-12-Ado-OH
Purity
≥98.0% (TLC)
Packaging
500mg
Price
$125
Updated
2025/07/31
TRC
Product number
B602715
Product name
Boc-12-aminododecanoicAcid
Packaging
1g
Price
$175
Updated
2021/12/16
Usbiological
Product number
235834
Product name
Boc-12-aminododecanoic acid
Packaging
1g
Price
$200
Updated
2021/12/16
Usbiological
Product number
264982
Product name
Boc-12-aminododecanoic acid
Packaging
1g
Price
$360
Updated
2021/12/16
Iris Biotech GmbH
Product number
BAA1323
Product name
Boc-12-Ado-OH
Packaging
5G
Price
$324
Updated
2021/12/16
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BOC-12-ADO-OH Chemical Properties,Usage,Production

Description

Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

BOC-12-ADO-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-12-ADO-OH Suppliers

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View Lastest Price from BOC-12-ADO-OH manufacturers

Career Henan Chemica Co
Product
BOC-12-ADO-OH 18934-81-1
Price
US $0.80-1.80/KG
Min. Order
1KG
Purity
95%~99.99%
Supply Ability
10 MT/ Month
Release date
2020-11-04

18934-81-1, BOC-12-ADO-OHRelated Search:


  • 12-(BOC-AMINO)DODECANOIC ACID
  • BOC-12-ADO-OH
  • BOC-12-AMINODODECANOIC ACID
  • BOC-12-AMINOLAURIC ACID
  • BOC-NH-(CH2)11-COOH
  • N-TERT-BUTYLOXYCARBONYL-12-AMINO-DODECANOIC ACID
  • T-BUTOXYCARBONYL-12-AMINODODECANOIC ACID
  • T-BUTOXYCARBONYL-12-AMINOLAURIC ACID
  • N-T-BUTYLOXYCARBONYL-12-AMINO-DODECANOIC ACID
  • N-tert-Butoxycarbonyl-12-aminododecanoic acid
  • Boc-12-Ado-OH >=98.0% (TLC)
  • N-Boc-12-aminododecanoic acid
  • 12-{[(tert-butoxy)carbonyl]amino}dodecanoic acid
  • Dodecanoic acid, 12-[[(1,1-dimethylethoxy)carbonyl]amino]-
  • 12-[(2-methylpropan-2-yl)oxycarbonylamino]dodecanoic acid
  • 12-Boc-aminododecanic acid
  • 12-((tert-Butoxycarbonyl)amino)dodecanoic acid - [B94809]
  • 18934-81-1
  • C17H33NO4
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • Peptide Synthesis
  • Linear Core Amino Acids
  • Amino Acids