ChemicalBook > CAS DataBase List > 6,7-dimethylisatin

6,7-dimethylisatin

Product Name
6,7-dimethylisatin
CAS No.
20205-43-0
Chemical Name
6,7-dimethylisatin
Synonyms
6,7-dimethylisatin;1H-Indole-2,3-dione, 6,7-dimethyl-;6,7-dimethyl-1H-indole-2,3-dione(SALTDATA: FREE)
CBNumber
CB51074115
Molecular Formula
C10H9NO2
Formula Weight
175.18
MOL File
20205-43-0.mol
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6,7-dimethylisatin Property

Melting point:
252 °C
Density 
1.250±0.06 g/cm3(Predicted)
pka
10.43±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D474480
Product name
6,7-Dimethyl-1H-indole-2,3-dione
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD114580
Product name
6,7-Dimethyl-1H-indole-2,3-dione
Packaging
250mg
Price
$57.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD114580
Product name
6,7-Dimethyl-1H-indole-2,3-dione
Packaging
500mg
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
030130
Product name
6,7-Dimethyl-1H-indole-2,3-dione
Packaging
1g
Price
$215
Updated
2021/12/16
AK Scientific
Product number
0364AB
Product name
6,7-Dimethylindoline-2,3-dione
Packaging
500mg
Price
$244
Updated
2021/12/16
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6,7-dimethylisatin Chemical Properties,Usage,Production

Uses

6,7-Dimethylisatin (compound 1l), an Isatin (HY-Y0265) analogue, is a potent MAO inhibitor with IC50s of 20.3 μM and 6.74 μM for MAO-A and MAO-B, respectively. 6,7-Dimethylisatin has the potential for depression, Alzheimer's disease and Parkinson's disease research[1].

IC 50

MAO-A: 20.3 μM (IC50); MAO-B: 6.74 μM (IC50)

References

[1] Izak F Prinsloo, et al. The evaluation of isatin analogues as inhibitors of monoamine oxidase. Chem Biol Drug Des. 2023 Nov;102(5):1067-1074. DOI:10.1111/cbdd.14304

6,7-dimethylisatin Preparation Products And Raw materials

Raw materials

Preparation Products

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6,7-dimethylisatin Suppliers

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