6,7-dimethylisatin
- Product Name
- 6,7-dimethylisatin
- CAS No.
- 20205-43-0
- Chemical Name
- 6,7-dimethylisatin
- Synonyms
- 6,7-dimethylisatin;1H-Indole-2,3-dione, 6,7-dimethyl-;6,7-dimethyl-1H-indole-2,3-dione(SALTDATA: FREE)
- CBNumber
- CB51074115
- Molecular Formula
- C10H9NO2
- Formula Weight
- 175.18
- MOL File
- 20205-43-0.mol
6,7-dimethylisatin Property
- Melting point:
- 252 °C
- Density
- 1.250±0.06 g/cm3(Predicted)
- pka
- 10.43±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D474480
- Product name
- 6,7-Dimethyl-1H-indole-2,3-dione
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FD114580
- Product name
- 6,7-Dimethyl-1H-indole-2,3-dione
- Packaging
- 250mg
- Price
- $57.5
- Updated
- 2021/12/16
- Product number
- FD114580
- Product name
- 6,7-Dimethyl-1H-indole-2,3-dione
- Packaging
- 500mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 030130
- Product name
- 6,7-Dimethyl-1H-indole-2,3-dione
- Packaging
- 1g
- Price
- $215
- Updated
- 2021/12/16
- Product number
- 0364AB
- Product name
- 6,7-Dimethylindoline-2,3-dione
- Packaging
- 500mg
- Price
- $244
- Updated
- 2021/12/16
6,7-dimethylisatin Chemical Properties,Usage,Production
Uses
6,7-Dimethylisatin (compound 1l), an Isatin (HY-Y0265) analogue, is a potent MAO inhibitor with IC50s of 20.3 μM and 6.74 μM for MAO-A and MAO-B, respectively. 6,7-Dimethylisatin has the potential for depression, Alzheimer's disease and Parkinson's disease research[1].
IC 50
MAO-A: 20.3 μM (IC50); MAO-B: 6.74 μM (IC50)
References
[1] Izak F Prinsloo, et al. The evaluation of isatin analogues as inhibitors of monoamine oxidase. Chem Biol Drug Des. 2023 Nov;102(5):1067-1074. DOI:10.1111/cbdd.14304
6,7-dimethylisatin Preparation Products And Raw materials
Raw materials
Preparation Products
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