emivirine
- Product Name
- emivirine
- CAS No.
- 149950-60-7
- Chemical Name
- emivirine
- Synonyms
- MKC 442;DRG0302;DRG 0302;DRG-0302;emivirine;6-benzyl-1-(ethoxymethyl)-5-isopropyluracil;1-(Ethoxymethyl)-6-benzyl-5-isopropyluracil;2,4(1H,3H)-Pyrimidinedione, 1-(ethoxymethyl)-5-(1-methylethyl)-6-(phenylmethyl)-
- CBNumber
- CB51074443
- Molecular Formula
- C17H22N2O3
- Formula Weight
- 302.37
- MOL File
- 149950-60-7.mol
emivirine Property
- Melting point:
- 109.1-110.7 °C(Solv: ethanol (64-17-5); water (7732-18-5))
- Density
- 1.133±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 9.46±0.40(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CM312567
- Product name
- 6-Benzyl-1-(ethoxymethyl)-5-isopropylpyrimidine-2,4(1H,3H)-dione
- Purity
- 95%
- Packaging
- 1g
- Price
- $693
- Updated
- 2021/12/16
- Product number
- 149950607
- Product name
- 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil
- Packaging
- 50mg
- Price
- $819
- Updated
- 2021/12/16
- Product number
- CD11251087
- Product name
- 6-Benzyl-1-(ethoxymethyl)-5-isopropylpyrimidine-2,4(1H,3H)-dione
- Purity
- 95+%
- Packaging
- 50mg
- Price
- $1080
- Updated
- 2021/12/16
- Product number
- 149950607
- Product name
- 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil
- Packaging
- 250mg
- Price
- $2317.59
- Updated
- 2021/12/16
emivirine Chemical Properties,Usage,Production
Uses
Treatment of HIV-1 infections (non-nucleoside reverse transcriptase inhibitor).
Uses
Emivirine can be used to treat disease cause by SARS-CoV-2
Definition
ChEBI: A pyrimidone that is uracil which is substituted at positions 1, 5 and 6 by ethoxymethyl, isopropyl, and benzyl groups, respectively. A non-nucleoside inhibitor of HIV-1 reverse transcriptase, emivirine was an unsuccessful experimental agent for the treatm nt of HIV.
brand name
Coactinon (Mitsubishi Chemical Corporation, Japan).
Hazard
Moderately toxic by ingestion.
Safety Profile
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.