2-CHLORO-5-ETHOXYPYRIDINE
- Product Name
- 2-CHLORO-5-ETHOXYPYRIDINE
- CAS No.
- 856851-48-4
- Chemical Name
- 2-CHLORO-5-ETHOXYPYRIDINE
- Synonyms
- 2-CHLORO-5-ETHOXYPYRIDINE;Pyridine, 2-chloro-5-ethoxy-
- CBNumber
- CB51076083
- Molecular Formula
- C7H8ClNO
- Formula Weight
- 157.6
- MOL File
- Mol file
2-CHLORO-5-ETHOXYPYRIDINE Property
- Boiling point:
- 92 °C(Press: 29 Torr)
- Density
- 1.166±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -2.22±0.10(Predicted)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C433315
- Product name
- 2-Chloro-5-ethoxypyridine
- Packaging
- 250mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- OR913408
- Product name
- 2-Chloro-5-ethoxypyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $385
- Updated
- 2021/12/16
- Product number
- Z5197
- Product name
- 2-Chloro-5-ethoxypyridine
- Packaging
- 250mg
- Price
- $138
- Updated
- 2021/12/16
- Product number
- OR913408
- Product name
- 2-Chloro-5-ethoxypyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- Z5197
- Product name
- 2-Chloro-5-ethoxypyridine
- Packaging
- 5g
- Price
- $707
- Updated
- 2021/12/16
2-CHLORO-5-ETHOXYPYRIDINE Chemical Properties,Usage,Production
Synthesis
41288-96-4
75-03-6
856851-48-4
GENERAL STEPS: To a stirred N,N-dimethylformamide (30 mL) solution of 6-chloropyridin-3-ol (3.0 g, 23.2 mmol) at 0 °C, ethyl iodide (4.33 g, 27.8 mmol, 2.22 mL) and potassium carbonate (9.60 g, 69.6 mmol) were sequentially added. The reaction mixture was gradually warmed to 40 °C and stirred continuously at this temperature for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of water (30 mL) and subsequently extracted with ethyl acetate (60 mL x 3). The organic phases were combined, washed with saturated aqueous sodium chloride (30 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the target product 2-chloro-5-ethoxypyridine (3.30 g, 20.9 mmol, 90% yield) as a yellow solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.97 (d, J=2.9Hz, 1H), 7.17-7.07 (m, 2H), 3.99 (q, J=7.0Hz, 2H), 1.36 (t, J=7.0Hz, 3H).
References
[1] Patent: WO2018/81167, 2018, A1. Location in patent: Page/Page column 231; 232; 241
2-CHLORO-5-ETHOXYPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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