1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE

Product Name: 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE
CAS No.: 120143-22-8
Chemical Name: 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE
Synonyms: 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE;1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-D-ribofuranose ;1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose;1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl) benzoyl-L-ribofuranose;1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-D-ribofuranose >=95% (HPLC);1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-D-ribofuranose
CBNumber: CB51091130
Molecular Formula: C17H19N3O7
Formula Weight: 377.351
MOL File: 120143-22-8.mol

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1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE Property

storage temp.: 2-8°C
form: powder
optical activity: [α]/D +11.0±2.0°, c = 1 in chloroform
BRN: 7317070

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36/37
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 712825
Product name: 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-D-ribofuranose
Purity: ≥95% (HPLC)
Packaging: 100mg
Price: $224
Updated: 2023/01/07

Usbiological

Product number: 292999
Product name: 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-toluoyl-D-ribofuranose
Packaging: 50mg
Price: $382
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MD04222
Product name: 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-toluoyl-D-ribofuranose
Packaging: 500mg
Price: $475
Updated: 2021/12/16

AK Scientific

Product number: 3418DN
Product name: 1,2-DI-O-Acetyl-3-azido-3-deoxy-5-O-toluoyl-D-ribofuranose
Packaging: 500mg
Price: $691
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MD04222
Product name: 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-toluoyl-D-ribofuranose
Packaging: 1g
Price: $892.5
Updated: 2021/12/16

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1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE Chemical Properties,Usage,Production

Uses

1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

reaction suitability

reaction type: click chemistry

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE Suppliers

China 13 India 1 United Kingdom 2 United States 4 Global 20

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Merck KGaA

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120143-22-8, 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSERelated Search:

5-O-Benzoyl-1,2-di-O-acetyl-3-deoxy-D-ribofuranose 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE

1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE

1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-D-ribofuranose

1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl)benzoyl-D-ribofuranose

1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(4-methyl) benzoyl-L-ribofuranose

1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-D-ribofuranose >=95% (HPLC)

1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-(p-toluoyl)-<sc>D</sc>-ribofuranose

120143-22-8