Ethyl 5-amino-4-phenylisoxazole-3-carboxylate
- Product Name
- Ethyl 5-amino-4-phenylisoxazole-3-carboxylate
- CAS No.
- 53983-15-6
- Chemical Name
- Ethyl 5-amino-4-phenylisoxazole-3-carboxylate
- Synonyms
- Ethyl 5-amino-4-phenyl-3-isoxazolecarboxylate;ethyl 5-amino-4-phenyl-1,2-oxazole-3-carboxylate;5-amino-4-phenyl-3-Isoxazolecarboxylic acid ethyl ester;3-Isoxazolecarboxylic acid, 5-amino-4-phenyl-, ethyl ester
- CBNumber
- CB51116574
- Molecular Formula
- C12H12N2O3
- Formula Weight
- 232.24
- MOL File
- 53983-15-6.mol
Ethyl 5-amino-4-phenylisoxazole-3-carboxylate Property
- storage temp.
- 2-8°C(protect from light)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- COR0004031
- Product name
- ETHYL 5-AMINO-4-PHENYLISOXAZOLE-3-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $386.4
- Updated
- 2021/12/16
- Product number
- 3439AQ
- Product name
- Ethyl5-amino-4-phenylisoxazole-3-carboxylate
- Packaging
- 1g
- Price
- $405.2
- Updated
- 2021/12/16
- Product number
- COR0004031
- Product name
- ETHYL 5-AMINO-4-PHENYLISOXAZOLE-3-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1119.71
- Updated
- 2021/12/16
- Product number
- COR0004031
- Product name
- ETHYL 5-AMINO-4-PHENYLISOXAZOLE-3-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1379.44
- Updated
- 2021/12/16
- Product number
- CM253517
- Product name
- Ethyl5-amino-4-phenylisoxazole-3-carboxylate
- Purity
- 95+%
- Packaging
- 5g
- Price
- $645
- Updated
- 2021/12/16
Ethyl 5-amino-4-phenylisoxazole-3-carboxylate Chemical Properties,Usage,Production
Synthesis
1134-71-0
53983-15-6
General procedure for the synthesis of ethyl 5-amino-4-phenylisoxazole-3-carboxylate from the compound (CAS: 1134-71-0): phenylpropyl derivative 1 (12 mmol), hydroxylamine hydrochloride (1.66 g, 24 mmol) and 70 mL of ethanol were mixed and heated and refluxed for 12 hours. Upon completion of the reaction, the ethanol was removed by distillation under reduced pressure. Subsequently, 50 mL of ethyl acetate and 10 mL of 10% sodium carbonate solution were added to the residue and mixed thoroughly to separate the organic phase. The organic phase was washed with saturated sodium chloride solution and dried with anhydrous sodium sulfate. Finally, the ethyl acetate was removed by evaporation under reduced pressure to give 2.48 g of white powdery solid product in 89.11% yield.
References
[1] Patent: CN105777661, 2016, A. Location in patent: Paragraph 0041; 0042; 0043
Ethyl 5-amino-4-phenylisoxazole-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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