Nicotredole
- Product Name
- Nicotredole
- CAS No.
- 29876-14-0
- Chemical Name
- Nicotredole
- Synonyms
- tryptamide;Nicotredole;N-[2-(3-indolyl)ethyl]nicotinamide;N-(2-(1H-Indol-3-yl)ethyl)nicotinaMide;N-[2-(1H-indol-3-yl)ethyl]pyridine-3-carboxamide;3-Pyridinecarboxamide, N-[2-(1H-indol-3-yl)ethyl]-;anti-inflammatory,Nicotredole,analgesic,ulcerogenic,inhibit,Inhibitor
- CBNumber
- CB51116903
- Molecular Formula
- C16H15N3O
- Formula Weight
- 265.31
- MOL File
- 29876-14-0.mol
Nicotredole Property
- Boiling point:
- 408.53°C (rough estimate)
- Density
- 1.0944 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO: 25 mg/mL (94.23 mM)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 074574
- Product name
- N-(2-(1H-Indol-3-yl)ethyl)nicotinamide
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $416
- Updated
- 2021/12/16
- Product number
- CHM1002549
- Product name
- N-(2-(1H-INDOL-3-YL)ETHYL)NICOTINAMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.69
- Updated
- 2021/12/16
- Product number
- W5233
- Product name
- Nicotredole
- Packaging
- 5g
- Price
- $698
- Updated
- 2021/12/16
- Product number
- 074574
- Product name
- N-(2-(1H-Indol-3-yl)ethyl)nicotinamide
- Purity
- 95+%
- Packaging
- 1g
- Price
- $899
- Updated
- 2021/12/16
- Product number
- 074574
- Product name
- N-(2-(1H-Indol-3-yl)ethyl)nicotinamide
- Purity
- 95+%
- Packaging
- 5g
- Price
- $2411
- Updated
- 2021/12/16
Nicotredole Chemical Properties,Usage,Production
Biological Activity
Nicotredole (Tryptamide) is an orally active anti-inflammatory analgesic. It showed significant anti-inflammatory effects comparable to Phenylbutazone.
in vitro
Nicotredole inhibits prostaglandin synthetase activity in vitro.
in vivo
Nicotredole produces antiinflammatory effects in carrageenin-induced rat paw oedema.
It reverses pyrogen-induced hyperthermia in rats, elicits analgesic effects in rats, prolongs the time of hexobarbital sleep in rats and inhibits locomotor activity in rats and mice.
Nicotredole (ip) has LD50s of 1260 mg/kg and 1980 mg/kg for male rats and male mice, respectively.
Nicotredole (po) has LD50s of 8.5 g/kg and 9.3 g/kg for male rats and male mice, respectively.
Nicotredole (25 mg/kg; po or ip) undergoes fast absorption (t 1/2 =4.92-17.5 min) and elimination (t 1/2 =55.72-74.52 min), can reach C max (11-13 μg/cm 3 ) after 30 min, and gives AUC values in the range of 21.40-27.30 (μg?h/cm 3 ).
Nicotredole Preparation Products And Raw materials
Raw materials
Preparation Products
Nicotredole Suppliers
View Lastest Price from Nicotredole manufacturers
- Product
- Nicotredole 29876-14-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-10