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Hepronicate

Product Name
Hepronicate
CAS No.
7237-81-2
Chemical Name
Hepronicate
Synonyms
Megrin;Hepronicate;1,1,1-Heptanetriyltris(methanol)tris(nicotinate);1,1,1-Heptanetriyltris(methanol) tris(nicotinate);2-Hydroxymethyl-2-hexyl-1,3-propanediol trinicotinate;Bis(nicotinic acid)2-hexyl-2-(nicotinoyloxymethyl)-1,3-propanediyl ester;3-Pyridinecarboxylic acid, 1,1'-[2-hexyl-2-[[(3-pyridinylcarbonyl)oxy]methyl]-1,3-propanediyl] ester
CBNumber
CB51117157
Molecular Formula
C28H31N3O6
Formula Weight
505.56
MOL File
7237-81-2.mol
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Hepronicate Property

Melting point:
94-96°
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0002898
Product name
HEPRONICATE
Purity
95.00%
Packaging
5MG
Price
$505.21
Updated
2021/12/16
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Hepronicate Chemical Properties,Usage,Production

Originator

Megrin,Yoshitomi,Japan,1972

Definition

ChEBI: Hepronicate is an organic molecular entity.

Manufacturing Process

In 50 ml of pyridine were dissolved 50 grams of nicotinic acid and 50 grams of p-toluene-sulfonyl chloride. While stirring, the mixture gradually became hot and colorless, and finally solidified. To the mixture was added dropwise a solution of 19 grams of 2-hexyl-2-(hydroxymethyl)-1,3-propanediol in 400 ml of pyridine at a temperature below 80°C. The mixture was heated at 115° to 125°C on an oil bath for 1 hour. After cooling, the mixture was poured into 300 ml of ice water, and extracted with toluene. The toluene layer was washed in sequence with water, aqueous sodium carbonate and water, dried over potassium carbonate, and then the toluene was distilled off. The oily residue was crystallized from ethanol to give 30 grams of 2-hexyl-2-(hydroxymethyl)- 1,3-propanediol trinicotinate, melting at 94° to 96°C. The yield was 59.5%.

Therapeutic Function

Vasodilator

Hepronicate Preparation Products And Raw materials

Raw materials

Preparation Products

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Hepronicate Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24648
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19863
Advantage
58

7237-81-2, HepronicateRelated Search:


  • 1,1,1-Heptanetriyltris(methanol) tris(nicotinate)
  • 1,1,1-Heptanetriyltris(methanol)tris(nicotinate)
  • 2-Hydroxymethyl-2-hexyl-1,3-propanediol trinicotinate
  • Bis(nicotinic acid)2-hexyl-2-(nicotinoyloxymethyl)-1,3-propanediyl ester
  • Megrin
  • Hepronicate
  • 3-Pyridinecarboxylic acid, 1,1'-[2-hexyl-2-[[(3-pyridinylcarbonyl)oxy]methyl]-1,3-propanediyl] ester
  • 7237-81-2