Adibendan

Product Name: Adibendan
CAS No.: 100510-33-6
Chemical Name: Adibendan
Synonyms: BM-14478;Adibendan;Adibendan, 10 mM in DMSO;7,7-Dimethyl-2-(pyridin-4-yl)-3H,5H,6H,7H-imidazo[4,5-F]indol-6-one;5,7-Dihydro-7,7-dimethyl-2-(pyridin-4-yl)pyrrolo[2,3-f]benzimidazol-6(1H)-one;Pyrrolo[2,3-f]benzimidazol-6(3H)-one, 5,7-dihydro-7,7-dimethyl-2-(4-pyridinyl)-
CBNumber: CB51117430
Molecular Formula: C16H14N4O
Formula Weight: 278.314
MOL File: 100510-33-6.mol

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Adibendan Property

Melting point:: 285-288 °C(Solv: methanol (67-56-1))
Density: 1.302±0.06 g/cm3(Predicted)
pka: 9.72±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0010618
Product name: ADIBENDAN
Purity: 95.00%
Packaging: 5MG
Price: $499.65
Updated: 2021/12/16

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Adibendan Chemical Properties,Usage,Production

Uses

Adibendan (BM 14478), a benzimidazole derivative, is an orally active, selective phosphodiesterase III (PDE III) activity inhibitor (IC50=2.0 μM). Adibendan has IC50 values more than 60-fold higher for the inhibition of PDE I or II. Adibendan is a new cardiotonic agent[1].

References

[1] T Bethke, et al. Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts. Naunyn Schmiedebergs Arch Pharmacol. 1988 May;337(5):576-82. DOI:10.1007/BF00182735

Adibendan Preparation Products And Raw materials

Raw materials

Preparation Products

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Adibendan Suppliers

China 12 United Kingdom 1 United States 5 Global 18

Capot Chemical Co., Ltd

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100510-33-6, AdibendanRelated Search:

2-(4-PYRIDYL)BENZIMIDAZOLE 4-(1H-IMIDAZOL-2-YL)-PYRIDINE N-(1H-BENZOIMIDAZOL-5-YL)-ACETAMIDE Adibendan

Adibendan

5,7-Dihydro-7,7-dimethyl-2-(pyridin-4-yl)pyrrolo[2,3-f]benzimidazol-6(1H)-one

BM-14478

Pyrrolo[2,3-f]benzimidazol-6(3H)-one, 5,7-dihydro-7,7-dimethyl-2-(4-pyridinyl)-

Adibendan, 10 mM in DMSO

7,7-Dimethyl-2-(pyridin-4-yl)-3H,5H,6H,7H-imidazo[4,5-F]indol-6-one

100510-33-6