Tebufelone

Product Name: Tebufelone
CAS No.: 112018-00-5
Chemical Name: Tebufelone
Synonyms: NE-11740;Tebufelone;Tebufelone, 10 mM in DMSO;1-(3,5-Ditert-butyl-4-hydroxyphenyl)-5-hexyn-1-one;5-Hexyn-1-one, 1-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-
CBNumber: CB51117793
Molecular Formula: C20H28O2
Formula Weight: 300.44
MOL File: 112018-00-5.mol

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Tebufelone Property

form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0025116
Product name: TEBUFELONE
Purity: 95.00%
Packaging: 5MG
Price: $499.8
Updated: 2021/12/16

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Tebufelone Chemical Properties,Usage,Production

Uses

Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties[1][2].

IC 50

COX-2; 5-LO

References

[1] S M Weisman, et al. Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism. Agents Actions. 1994 May;41(3-4):156-63. DOI:10.1007/BF02001910
[2] Sebastian Braun, et al. Carborane-Based Tebufelone Analogs and Their Biological Evaluation In Vitro. ChemMedChem. 2023 Jul 17;18(14):e202300206. DOI:10.1002/cmdc.202300206

Tebufelone Preparation Products And Raw materials

Raw materials

Preparation Products

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Tebufelone Suppliers

China 9 United Kingdom 1 United States 2 Global 12

Leancare Ltd.

Tel: --
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Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

112018-00-5, TebufeloneRelated Search:

Montelukast 3,5-Di-tert-butyl-4-hydroxybenzaldehyde 1-M-TOLYL-PENTAN-1-ONE Tebufelone 3,5-DI-TERT-BUTYL-4-HYDROXYACETOPHENONE

Tebufelone

1-(3,5-Ditert-butyl-4-hydroxyphenyl)-5-hexyn-1-one

NE-11740

5-Hexyn-1-one, 1-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-

Tebufelone, 10 mM in DMSO

112018-00-5