ChemicalBook > CAS DataBase List > Tebufelone
Tebufelone
- Product Name
- Tebufelone
- CAS No.
- 112018-00-5
- Chemical Name
- Tebufelone
- Synonyms
- NE-11740;Tebufelone;Tebufelone, 10 mM in DMSO;1-(3,5-Ditert-butyl-4-hydroxyphenyl)-5-hexyn-1-one;5-Hexyn-1-one, 1-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-
- CBNumber
- CB51117793
- Molecular Formula
- C20H28O2
- Formula Weight
- 300.44
- MOL File
- 112018-00-5.mol
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Tebufelone Property
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0025116
- Product name
- TEBUFELONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.8
- Updated
- 2021/12/16
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Tebufelone Chemical Properties,Usage,Production
Uses
Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties[1][2].
IC 50
COX-2; 5-LO
References
[1] S M Weisman, et al. Effects of tebufelone (NE-11740), a new anti-inflammatory drug, on arachidonic acid metabolism. Agents Actions. 1994 May;41(3-4):156-63. DOI:10.1007/BF02001910
[2] Sebastian Braun, et al. Carborane-Based Tebufelone Analogs and Their Biological Evaluation In Vitro. ChemMedChem. 2023 Jul 17;18(14):e202300206. DOI:10.1002/cmdc.202300206
Tebufelone Preparation Products And Raw materials
Raw materials
Preparation Products
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Tebufelone Suppliers
- Tel
- --
- Fax
- --
- sales@2apharmachem.com
- Country
- United States
- ProdList
- 6137
- Advantage
- 39
- Tel
- --
- Fax
- --
- sales@3bsc.com
- Country
- United States
- ProdList
- 6718
- Advantage
- 47
112018-00-5, TebufeloneRelated Search:
Montelukast
3,5-Di-tert-butyl-4-hydroxybenzaldehyde
1-M-TOLYL-PENTAN-1-ONE
Tebufelone
3,5-DI-TERT-BUTYL-4-HYDROXYACETOPHENONE