4-CYANO-3,5-DIFLUORO BENZALDEHYDE
- Product Name
- 4-CYANO-3,5-DIFLUORO BENZALDEHYDE
- CAS No.
- 433939-88-9
- Chemical Name
- 4-CYANO-3,5-DIFLUORO BENZALDEHYDE
- Synonyms
- 2,6-DIFLUORO-4-FORMYLBENZONITRILE;Benzonitrile,2,6-difluoro-4-formyl-;4'-Chloro-2,2,3-trifluoroacetophenone
- CBNumber
- CB51119287
- Molecular Formula
- C8H3F2NO
- Formula Weight
- 167.11
- MOL File
- 433939-88-9.mol
4-CYANO-3,5-DIFLUORO BENZALDEHYDE Property
- Melting point:
- 48-50℃
- Boiling point:
- 263℃
- Density
- 1.35
- Flash point:
- 113℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D456598
- Product name
- 2,6-difluoro-4-formylbenzonitrile
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- PC201253
- Product name
- 2,6-Difluoro-4-formylbenzonitrile
- Purity
- 98%
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- W6274
- Product name
- 2,6-Difluoro-4-formylbenzonitrile
- Packaging
- 1g
- Price
- $131
- Updated
- 2021/12/16
- Product number
- FD16001
- Product name
- 2,6-Difluoro-4-formylbenzonitrile
- Packaging
- 50mg
- Price
- $40
- Updated
- 2021/12/16
- Product number
- HCH0049733
- Product name
- 2,6-DIFLUORO-4-FORMYLBENZONITRILE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $195.41
- Updated
- 2021/12/16
4-CYANO-3,5-DIFLUORO BENZALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
Light yellow Cryst
Synthesis
479621-01-7
433939-88-9
2,6-Difluoro-4-[(methylsulfinyl)(methylthio)methyl]benzonitrile (2.17 g, 8.32 mmol) was used as a raw material, which was dissolved in 90 mL of tetrahydrofuran (THF), followed by the addition of 3.5 mL of concentrated sulfuric acid. The reaction mixture was stirred at room temperature for 3 days. After completion of the reaction, the mixture was slowly poured into 450 mL of water and extracted three times with ethyl acetate (EtOAc). The organic phases were combined, washed twice sequentially with aqueous sodium bicarbonate and saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the target product 2,6-difluoro-4-formylphenyl cyanide. Yield: 1.36 g (98%). The structure of the product was confirmed by 13C NMR, where the carbon signal at 140.7 ppm showed the expected coupling pattern with two coupling constants of 260 Hz and 6.3 Hz, corresponding to ipso and meso coupling to the fluorine atom.1H NMR (400 MHz, CDCl3) δ 10.35 (s, 1H), 7.33 (m, 2H).
References
[1] Patent: US2004/19033, 2004, A1. Location in patent: Page/Page column 47
4-CYANO-3,5-DIFLUORO BENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-CYANO-3,5-DIFLUORO BENZALDEHYDE manufacturers
- Product
- 2,6-difluoro-4-formylbenzonitrile 433939-88-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-13
- Product
- 4-CYANO-3,5-DIFLUORO BENZALDEHYDE 433939-88-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12