ChemicalBook > CAS DataBase List > (S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE

(S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE

Product Name
(S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE
CAS No.
239483-09-1
Chemical Name
(S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE
Synonyms
(S)-2-(Aminoethyl)-1-Boc-pyrrolidine;(S)-1-Boc-2-(2-aminoethyl)pyrrolidine;(S)-2-(Aminoethyl)-1-Boc-pyrrolidine - [A14053];2-Ethyl-pyrrolidine-1-carboxylic acid tert-butyl ester;tert-butyl (s)-2-(2-aminoethyl)pyrrolidine-1-carboxylate;(S)-tert-butyl 2-(2-aminoethyl)pyrrolidine-1-carboxylate;tert-Butyl (2S)-2-(2-aminoethyl)-1-pyrrolidinecarboxylate;tert-butyl (2S)-2-(2-aMinoethyl)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 2-(2-aminoethyl)-, 1,1-dimethylethyl ester, (2S)-
CBNumber
CB51119641
Molecular Formula
C11H22N2O2
Formula Weight
214.3
MOL File
239483-09-1.mol
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(S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE Property

Boiling point:
297.5±13.0 °C(Predicted)
Density 
1.029
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
10.27±0.10(Predicted)
Appearance
light yellow liquid
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Safety

RIDADR 
UN3077
HazardClass 
8
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H401Toxic to aquatic life

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B900525
Product name
(S)-tert-Butyl2-(2-aminoethyl)pyrrolidine-1-carboxylate
Packaging
50mg
Price
$65
Updated
2021/12/16
TRC
Product number
B900525
Product name
(S)-tert-Butyl2-(2-aminoethyl)pyrrolidine-1-carboxylate
Packaging
500mg
Price
$330
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0000110
Product name
(S)-2-(2-AMINO-ETHYL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
Purity
95.00%
Packaging
250MG
Price
$228.9
Updated
2021/12/16
Synthonix
Product number
A14053
Product name
(S)-2-(Aminoethyl)-1-Boc-pyrrolidine
Purity
95+%
Packaging
1g
Price
$240
Updated
2021/12/16
Matrix Scientific
Product number
125146
Product name
(S)-2-(Aminoethyl)-1-Boc-pyrrolidine
Purity
95+%
Packaging
1g
Price
$545
Updated
2021/12/16
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(S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE Chemical Properties,Usage,Production

Synthesis

142253-50-7

239483-09-1

Step d: Synthesis of tert-butyl (S)-2-(2-aminoethyl)pyrrolidine-1-carboxylate. The product of step c, tert-butyl (S)-2-(cyanomethyl)pyrrolidine-1-carboxylate (1.45 g, 6.9 mmol) was suspended in ammonia saturated methanol (50 ml) and Raney-Nickel (ca. 1.0 g) and hexachloroplatinic acid (IV) hydrate (80 mg dissolved in 1 ml of water) were added. The mixture was placed in a Parr reaction flask and stirred under hydrogen pressure (~40 psi) for 24 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was evaporated. The crude product was purified by fast chromatography (eluent: dichloromethane:methanol:ammonia (880) 90:10:1) to afford tert-butyl (S)-2-(2-aminoethyl)pyrrolidine-1-carboxylate (1.18 g, 80% yield).1H NMR (CDCl3) δ: 3.90 (1H, m), 3.30 (2H, m), 2.71 (2H, t). 1.87-1.45 (17H, m).

References

[1] Patent: EP1056733, 2004, B1. Location in patent: Page 34-35
[2] Patent: WO2006/116764, 2006, A1. Location in patent: Page/Page column 121; 133-134
[3] Tetrahedron Letters, 1994, vol. 35, # 47, p. 8805 - 8808
[4] Patent: WO2004/58705, 2004, A2. Location in patent: Page 40-42
[5] Organic and Biomolecular Chemistry, 2010, vol. 8, # 16, p. 3742 - 3750

(S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE Suppliers

China 34 India 2 Switzerland 2 United Kingdom 1 United States 12 Global 51
Achemica
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contact@achemica.com
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Switzerland
ProdList
6155
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50
Biosynth AG
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welcome@biosynth.ch
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Switzerland
ProdList
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239483-09-1, (S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE Related Search:

2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE 1,8-DIAZA-SPIRO[4.5]DECANE-1-CARBOXYLIC ACID TERT-BUTYL ESTER N-Boc-endo-3-aminotropane (S)-2-(AMINOETHYL)-1-N-BOC-PYRROLIDINE FMOC-D, L-ALA(3-PYRROLIDINYL-(2-N-BOC)) FMOC-D-ALA(3-PYRROLIDINYL-(2-N-BOC)) TERT-BUTYL 5-AMINO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE (2S,4S)-N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N'-T-BUTYLOXYCARBONYL-2-PYRROLIDINYLALANINE 2-[2-CARBOXY-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-ETHYL]-4-HYDROXY-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

  • (S)-tert-butyl 2-(2-aminoethyl)pyrrolidine-1-carboxylate
  • tert-butyl (2S)-2-(2-aMinoethyl)pyrrolidine-1-carboxylate
  • 2-Ethyl-pyrrolidine-1-carboxylic acid tert-butyl ester
  • tert-Butyl (2S)-2-(2-aminoethyl)-1-pyrrolidinecarboxylate
  • 1-Pyrrolidinecarboxylic acid, 2-(2-aminoethyl)-, 1,1-dimethylethyl ester, (2S)-
  • (S)-2-(Aminoethyl)-1-Boc-pyrrolidine
  • (S)-1-Boc-2-(2-aminoethyl)pyrrolidine
  • (S)-2-(Aminoethyl)-1-Boc-pyrrolidine - [A14053]
  • tert-butyl (s)-2-(2-aminoethyl)pyrrolidine-1-carboxylate
  • 239483-09-1