ChemicalBook > CAS DataBase List > 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
- Product Name
- 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
- CAS No.
- 821794-92-7
- Chemical Name
- 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
- Synonyms
- FMK;Fluoromethyl Ketone;RSK2 kinase inhibitor;FMK - RSK inhibitor Fmk;Fluoromethyl Ketone-MEA, FMK-MEA;1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-fluoroethanone;1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone;Ethanone, 1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoro-;1-[5-amino-9-(3-hydroxypropyl)-7-(4-methylphenyl)-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-8-yl]-2-fluoro-ethanone
- CBNumber
- CB51161837
- Molecular Formula
- C18H19FN4O2
- Formula Weight
- 342.37
- MOL File
- 821794-92-7.mol
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1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Property
- Density
- 1.36
- storage temp.
- Store at -20°C
- solubility
- insoluble in H2O; ≥17.1 mg/mL in DMSO; ≥28.7 mg/mL in EtOH
- form
- solid
- color
- White to light yellow
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Safety
- HS Code
- 2933998090
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N-Bromosuccinimide Price
Tocris
- Product number
- 4690
- Product name
- Fmk
- Purity
- ≥97%(HPLC)
- Packaging
- 10
- Price
- $214
- Updated
- 2021/12/16
TRC
- Product number
- F657735
- Product name
- FMK
- Packaging
- 1mg
- Price
- $110
- Updated
- 2021/12/16
Axon Medchem
- Product number
- Axon1848
- Product name
- FMK-RSKinhibitorFmk
- Purity
- 99%
- Packaging
- 1mg
- Price
- $82.5
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0648
- Product name
- FMK
- Purity
- 99.30%
- Packaging
- 2mg
- Price
- $132
- Updated
- 2021/12/16
Axon Medchem
- Product number
- Axon1848
- Product name
- FMK-RSKinhibitorFmk
- Purity
- 99%
- Packaging
- 5mg
- Price
- $137.5
- Updated
- 2021/12/16
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1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Chemical Properties,Usage,Production
Uses
FMK is a potent irreversible RSK1/2 inhibitor (IC50 = 15 nM). Inactivates the C-terminal auto-kinase domain activity. Suppresses RSK2 kinase activity in RSK2-expressing HNSCC cell lines. Reduces HNSCC cell invasive ability. Displays no effect on EGF-stimulated phosphorylation of ERK1 or ERK2.
target
RSK1
storage
Store at -20°C
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Preparation Products And Raw materials
Raw materials
Preparation Products
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1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Suppliers
- Tel
- --
- Fax
- --
- info@axonmedchem.com
- Country
- The Netherlands
- ProdList
- 477
- Advantage
- 30
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View Lastest Price from 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone manufacturers
Career Henan Chemical Co
- Product
- 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3- d]pyrimidin-6-yl]-2-fluoroethanone 821794-92-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-01