Amcinafide
- Product Name
- Amcinafide
- CAS No.
- 7332-27-6
- Chemical Name
- Amcinafide
- Synonyms
- Amcinafide;9-Fluoro-11β,21-dihydroxy-16α,17-[[(R)-1-phenylethylidene]bis(oxy)]pregna-1,4-diene-3,20-dione
- CBNumber
- CB51177993
- Molecular Formula
- C29H33FO6
- Formula Weight
- 496.572
- MOL File
- 7332-27-6.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0010671
- Product name
- AMCINAFIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.53
- Updated
- 2021/12/16
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Amcinafide Chemical Properties,Usage,Production
Originator
Amcinafide,Onbio Inc.
Uses
Anti-inflammatory.
Manufacturing Process
1 ml 72% perchloric acid was added to a suspension of 4 g triamcinolone in 100 ml of fresh distilled acetophenone and the mixture was stirred at a room temperature before all triamcinolone solved (for about 2 hours). The solution was neutralized with help of 8 ml of 1.1 N sodium hydroxide and sufficient quantity of sodium bicarbonate. Then chloroform and water were added. Organic layer was separated and concentrated in vacuum. The residue was recrystallized from acetone-hexane and thoroughly washed from acetophenone with hexane. Triamcinolone acetophenide (amicinafide) was prepared. It had MP: 281°-283°C (decomp.);αD 23 = +23°. (c = 0.98 in CHCl3).
Therapeutic Function
Antiinflammatory, Antiallergic
Amcinafide Preparation Products And Raw materials
Raw materials
Preparation Products
7332-27-6, AmcinafideRelated Search:
Triamcinolone acetonide
(S)-(-)-2-o-Benzylglycerinaldehyde
6(R),7-ISOPROPYLIDENE-HEPTANOL
Amcinafide
(4R)-4-(2-HYDROXYETHYL)-2-PHENYL-1,3-DIOXOLANE
2-BENZYLOXY-2-METHYLPROPAN-1-OL
Triamcinolone
Descinolone
2,2-Dimethyl-4-hexyl-1,3-dioxolane