2-Bromo-5-chlorophenol
- Product Name
- 2-Bromo-5-chlorophenol
- CAS No.
- 13659-23-9
- Chemical Name
- 2-Bromo-5-chlorophenol
- Synonyms
- 2-Bromo-5-chlorophen;Phenol,2-broMo-5-chloro-;2-Bromo-5-chlorophenol 98%;2-Bromo-5-chlorophenol, 98%;4-Chloro-2-hydroxybromobenzene
- CBNumber
- CB51180371
- Molecular Formula
- C6H4BrClO
- Formula Weight
- 207.45
- MOL File
- 13659-23-9.mol
2-Bromo-5-chlorophenol Property
- Boiling point:
- 222.2±20.0 °C(Predicted)
- Density
- 1.788±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- solid
- pka
- 7.47±0.10(Predicted)
- color
- White to off-white
Safety
- Hazard Codes
- Xi
- HS Code
- 2908190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B684138
- Product name
- 2-Bromo-5-chlorophenol
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR59899
- Product name
- 2-Bromo-5-chlorophenol
- Purity
- 97%
- Packaging
- 5g
- Price
- $58
- Updated
- 2021/12/16
- Product number
- 2601-D-X0
- Product name
- 2-Bromo-5-chlorophenol
- Purity
- 97%
- Packaging
- 5G
- Price
- $64
- Updated
- 2021/12/16
- Product number
- 074016
- Product name
- 2-Bromo-5-chlorophenol
- Purity
- 95+%
- Packaging
- 5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB64417
- Product name
- 2-Bromo-5-chlorophenol
- Packaging
- 10g
- Price
- $90
- Updated
- 2021/12/16
2-Bromo-5-chlorophenol Chemical Properties,Usage,Production
Chemical Properties
Pale yellow crystalline powder
Chemical Reactivity
The chemical reactions of 2-Bromo-5-chlorophenol include reactions with aminopyridine, isopropyl alcohol, chloroaniline, halophenols, dimethylamine, ethanolamine and toluidine. 2-Bromo-5-chlorophenol has been used as a reagent for the preparation of diethyl ethers and nitrates. This product has been used as a reagent for the synthesis of methyl groups and emulsifying agents for oil and water mixtures.
Synthesis
108-43-0
13659-23-9
The general procedure for the synthesis of 2-bromo-5-chlorophenol using 3-chlorophenol as starting material was as follows: 5.03 g (39.1 mmol) of 3-chlorophenol was dissolved in 20 mL of dichloromethane, and the solution was cooled under ice bath conditions. Subsequently, 6.25 g (39.1 mmol) of bromine was added slowly and dropwise. The reaction mixture was gradually warmed to room temperature and stirred continuously for 16 hours. After completion of the reaction, the reaction mixture was diluted with water and phase separation was carried out. The organic phase was dried with magnesium sulfate. The residue was purified by silica gel column chromatography with an eluent ratio of 3:2 dichloromethane to hexane solvent mixture. The elution grade containing the target product 2-bromo-5-chlorophenol was collected and concentrated under reduced pressure to give 2.04 g (25% yield) of the pure product. High-resolution mass spectrometry (HRMS) results: calculated value of C6H4OClBr (M+) was 205.9134; measured value was 205.9125. Elemental analysis (EA) results: calculated value of C, 34.74; H, 1.94; measured value of C, 34.74; H, 1.76.
References
[1] Patent: EP1204659, 2003, B1. Location in patent: Page/Page column 30
2-Bromo-5-chlorophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromo-5-chlorophenol manufacturers
- Product
- 2-Bromo-5-chlorophenol 13659-23-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg; 10kg; 100kg
- Release date
- 2019-08-30