ChemicalBook > CAS DataBase List > (R)-SEGPHOS

(R)-SEGPHOS

Reactions

Product Name: (R)-SEGPHOS
CAS No.: 244261-66-3
Chemical Name: (R)-SEGPHOS
Synonyms: segphos;(R)-SEGPHOS(R);(R)-(+)-SEGPHOS;(R)-SEGPHOS(R) >=94%;(R)-(+)-SEGPHOS(regR);(R)-(+)-SEGPHOS(R)-(+)-SEGPHOS;(R)-SEGPHOS^?;(R)-(+)-SEGPHOS^{®5,5'-Bis(diphenylphosphinoyl)-4,4'-di-1,3-biphenyl;4,4'-Bi-1,3-benzodioxole-5,5'-diylbis(diphenylphosphine)}
CBNumber: CB51180982
Molecular Formula: C38H28O4P2
Formula Weight: 610.59
MOL File: 244261-66-3.mol

Less

(R)-SEGPHOS Property

Melting point:: 168-172 °C
Boiling point:: 715.4±60.0 °C(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: Powder
color: off-white
optical activity: [α]20/D +11°, c = 0.5 in chloroform
InChIKey: RZZDRSHFIVOQAF-UHFFFAOYSA-N
SMILES: P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC2OCOC=2C=1C1C2OCOC=2C=CC=1P(C1C=CC=CC=1)C1C=CC=CC=1

Less

Safety

WGK Germany: 3
HS Code: 2932.99.7000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 692395
Product name: (R)-SEGPHOS?
Purity: ≥94%
Packaging: 100mg
Price: $37.06
Updated: 2025/07/31

TCI Chemical

Product number: S0930
Product name: (R)-(+)-SEGPHOS[R]
Purity: >99.0%(HPLC)
Packaging: 200mg
Price: $53
Updated: 2025/07/31

TCI Chemical

Product number: S0930
Product name: (R)-(+)-SEGPHOS[R]
Purity: >99.0%(HPLC)
Packaging: 1g
Price: $181
Updated: 2025/07/31

Strem Chemicals

Product number: 15-0136
Product name: (R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole, min. 98% (R)-(+)-SEGPHOS(R)
Packaging: 250mg
Price: $48
Updated: 2024/03/01

Strem Chemicals

Product number: 15-0136
Product name: (R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole, min. 98% (R)-(+)-SEGPHOS(R)
Packaging: 1g
Price: $142
Updated: 2024/03/01

Less

(R)-SEGPHOS Chemical Properties,Usage,Production

Reactions

Biaryl bisphosphine ligand with narrow dihedral angle. The SEGPHOS® ligand has been applied to a variety of metal catalyzed reactions. In many cases, yields and enantioselectivities, exceed results obtained earlier using BINAP.
As ruthenium complex, SEGPHOS® generally gives higher levels of chiral induction in asymmetric hydrogenations of α,β,and γ-functionalized ketones.
Used in Rh-catalyzed transformations such as: (a) 1,4-addition of boronic acids to coumarins, (b) addition of titanium reagents to imines,(c) cotrimerization of alkenes and acetylenes,10 (d)double [2+2+2] cycloaddition,11 (e) indanone formation.
Used in Pd-catalyzed transformations such as: (a) cycloaddition of 1,6-enyne,(b) arylative cyclization of allenyl aldehydes with boronic acids,13 (c) synthesis of chromans.
Used in Cu-catalyzed transformations such as: (a) nitroso Diels-Alder,(b) reductive aldol condensation,(c) conjugate reduction of unsaturated sulfones,and phophonates.
Iridium-catalyzed asymmetric hydrogenation of quinolines activated by chloroformates.
Iridium-catalyzed asymmetric transfer hydrogenation used in polyketide construction.
Rhodium-catalyzed asymmetric hydroarylation of 3-pyrrolines.
Palladium-catalyzed regio- and enantioselective dearomatization.

Uses

(R)-(+)-SEGPHOS? is a chelating ligand used to prepare coordination complex catalysts, such as its use in Pd catalysts for the enantioselective addition of diesters to 3,3-difluoropropenes, and in the Ni-based catalyst for the asymmetric propargylic amination of propargylic carbonates with an internal alkyne group.

(R)-SEGPHOS Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(R)-SEGPHOS Suppliers

China 98 India 2 Japan 2 Switzerland 1 United Kingdom 2 United States 9 Global 114

Henan Kaiyan Biotechnology Co. Ltd.

Tel: 0371-55676069 18137782046
Fax: 0371-55676069
Email: 1821614734@qq.com
Country: China
ProdList: 398
Advantage: 58

Xinxiang Runyu Material Co., Ltd.

Tel: 166-166-37336996 15690792173
Fax: 0373-7759608
Email: chenxi.song@runvmat.com
Country: China
ProdList: 285
Advantage: 55

Zhengzhou Kingorgchem Chemical Technology Co., Ltd.gy Co., Ltd.

Tel: 0371-65511006 18625597674
Email: sales@kingorgchem.com
Country: China
ProdList: 976
Advantage: 55

Zhengzhou HQ Material Co., Ltd.

Tel: 0371-67759225 13526468238
Email: sale@hqmat.com
Country: China
ProdList: 1256
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7471
Advantage: 65

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Tianjin Derchemist Science & Technology Co., Ltd.

Tel: 22-58627059 13920586291
Fax: 022-58620305
Email: zdcomcon@126.com
Country: China
ProdList: 3829
Advantage: 50

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sinocompound Catalysts Co., Ltd.

Tel: 0512-67216630 67216634
Fax: 0512-56316689
Email: sales@sinocompound.com
Country: China
ProdList: 271
Advantage: 64

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 15121041756
Email: xingui2022@126.com
Country: China
ProdList: 9979
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Chiral bio-compound co., Ltd.

Tel: 021-5068 3667/17749785980/1029026415; 17749785980
Fax: 021-50683667
Email: 1029026415@qq.com
Country: China
ProdList: 3397
Advantage: 58

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Panjin Infinity Scientific CO. LTD

Tel: 400-1062016 18612996721
Fax: QQ25788917
Email: hao@infsci.com
Country: China
ProdList: 327
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10110
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

LaaJoo

Tel: 021-60702684 18516024827
Email: huang.jiayi@sinocompound.com
Country: China
ProdList: 2280
Advantage: 58

Greenherbs Science and Technology Development Co., Ltd.

Tel: 010-61136123
Fax: +86 (10) 8857-9127
Email: pub02@greenherbs.com.cn
Country: China
ProdList: 4049
Advantage: 58

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Domole Scientific

Tel: 13275595566
Fax: -
Email: domole@infsci.com
Country: China
ProdList: 299
Advantage: 58

Shanghai Tube Pharmaceutical Co., Ltd.

Tel: 021-54338626 18017892860
Fax: 021-54338626
Email: sales@tubepharm.com
Country: China
ProdList: 2572
Advantage: 58

Shanghai Anyinuo Biomedical Technology Co., Ltd.

Tel: 021-34625901 18018851262;
Email: 420970979@qq.com
Country: China
ProdList: 5894
Advantage: 58

Suzhou Adelaide Chemical Technology Co., Ltd.

Tel: 15995785122
Email: 3003020078@qq.com
Country: China
ProdList: 1198
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Zhengzhou Alfa Chemical Co.,Ltd

Tel: +8618530059196
Email: sale04@alfachem.cn
Country: China
ProdList: 11784
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Jinan Ruisi Pharmaceutical Technology Co., LTD

Tel: 0531-0531-69900633 19963472814
Email: changyuan20@163.com
Country: China
ProdList: 2742
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Wuhan hongde yuexin pharmaceutical technology co. LTD

Tel: 027-83855391 13657260109
Fax: 027-83855391
Email: 2143879032@QQ.com
Country: China
ProdList: 1000
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Richest Group Ltd

Tel: 18017061086
Email: oled@richest-group.com
Country: CHINA
ProdList: 5600
Advantage: 58

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Tel: +86-021-61551413 +8618813727289
Email: contact@trustwe.com
Country: China
ProdList: 5743
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

wuhan zitai technology co.,ltd.

Tel: 13995588728
Email: 303957778@qq.com
Country: China
ProdList: 224
Advantage: 58

CHG Opto-Electronic Corporation Limited

Tel: 2537653158 16621191650
Fax: QQ 2537653158
Email: 2537653158@qq.com
Country: China
ProdList: 7301
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Less

View Lastest Price from (R)-SEGPHOS manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: (R)-SEGPHOS 244261-66-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 2000
Release date: 2025-07-29

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (R)-SEGPHOS 244261-66-3
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-25

XINXIANG RUNYU MATERIAL CO., LTD.

Product: (R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole,min.98%(R)-SEGPHOS 244261-66-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 500kg
Release date: 2021-11-30

244261-66-3, (R)-SEGPHOSRelated Search:

(S)-SunPhos (S)-(+)-2,2'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-6,6'-dimethoxy-1,1'-biphenyl,min.97% (R)-(+)-TolBINAP (R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis[bis(3,5-di-tert-butyl-4-methoxypheny R(+)-2 2'-BIS-(DIPHENYLPHOSPHINO)-6 6'-& (S)-(-)-2,2'-Bis[di(3,5-xylyl)phosphino]-1,1'-binaphthyl (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (R)-(+)-2,2'-Bis(di-i-propylphosphino)-6,6'-dimethoxy-1,1'-biphenyl,min.97% (R)-H8-BINAP (R)-DIFLUORPHOS(TM) (S)-(-)-2,2'-BIS(DI-P-TOLYLPHOSPHINO)-1,1'-BINAPHTHYL (R)-DTBM-SEGPHOS (R)-(+)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(R)-DM-SEGPHOS (S)-(-)-5,5'-Bis[di(3,5-xylyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DM-SEGPHOS N-[(1R,2R)-1,2-Diphenyl-2-(2-(4-Methylbenzyloxy)ethylaMino)-ethyl]-4-Methylbenzene sulfonaMide(chloro)rutheniuM(II) (R,R)-Ts-DENEB 1333981-84-2 Chloro{(R)-(+)-2,2'-bis[di(3,5-xylyl)phosphino]-1,1'-binaphthyl} [(2R)-(-)-1-(4-Methoxyphenyl)- 1 (4-Methoxyphenyl-kC)-3- Methyl-1,2-butanediaMine]rutheniuM(II) (R)-RUCY XylBINAP (S)-(-)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole,min.98%(S)-SEGPHOS (S)-(+)-5,5'-Bis[di(3,5-di-t-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole,min.98%(S)-DTBM-SEGPHOS

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole,min.98%(R)-SEGPHOS

(R)-(+)-5,5μ-Bis(diphenylphosphino)-4,4μ-bi-1,3-benzodioxole, [4(R)-(4,4μ-bi-1,3-benzodioxole)-5,5μ-diyl]bis[diphenylphosphine]

(R)-SEGPHOS(R)

(R)-(+)-SEGPHOS

Phosphine,1,1'-[(4R)-[4,4'-bi-1,3-benzodioxole]-5,5'-diyl]bis[1,1-diphenyl-

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole,(R)-(+)-SEGPHOS

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole

[(4R)-[4,4'-Bi-1,3-benzodioxole]-5,5'-diyl]bis[diphenylphosphine]

(R)-SEGPHOS(R) >=94%

(R)-(+)-SEGPHOS(regR)

(R)-(+)-SEGPHOS&reg

(R)-5,5'-Bis(diphenylphosphino)-4,4'-bibenzo[d][1,3]dioxole

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole, min. 98%

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole, min. 98% (R)-(+)-SEGPHOS(R)

1,1'-[(4R)-[4,4'-Bi-1,3-benzodioxole]-5,5'-diyl]bis[1,1-diphenylphosphine]

4,4'-Bi-1,3-benzodioxole-5,5'-diylbis(diphenylphosphine)

(R)-(+)-4,4'-Bis(diphenylphosphino)-3,3'-bi(1,2-methylenedioxybenzene)

(R)-(+)-SEGPHOS(R)-(+)-SEGPHOS

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole,min.98%

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole,min [(R)-Segphos]

(R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole [(R)-Segphos

1,1'-[(4R)-[4,4'-Bi-1,3-benzodioxole]-5,5'-diyl]bis[1,1-diphenylphosphine

(R)-SEGPHOS?

segphos

(R)-(+)-5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole, [4(R)-(4,4′-bi-1,3-benzodioxole)-5,5′-diyl]bis[diphenylphosphine], CAS 244261-66-3

5,5'-Bis(diphenylphosphinoyl)-4,4'-di-1,3-biphenyl

(R)-SEGPHOS / (R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole

244261-66-3

Chiral Phosphine

Segphos Series