ChemicalBook > CAS DataBase List > Palmitoyl Pentapeptide

Palmitoyl Pentapeptide

Product Name
Palmitoyl Pentapeptide
CAS No.
214047-00-4
Chemical Name
Palmitoyl Pentapeptide
Synonyms
PalMitoyl Pentapeptide-4;PALMITOYL;Palmitoyl Pentapeptide-4/3;Pla-KTTKS;WrinFix-P5P4;palmitoyl-KTTKS;Matrixyl(PAL-KTTKS);Rejuvenation peptide;Matrixyl 3000 powder;almitoyl pentapeptide
CBNumber
CB51214034
Molecular Formula
C39H75N7O10
Formula Weight
802.05
MOL File
214047-00-4.mol
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Palmitoyl Pentapeptide Property

Boiling point:
1120.1±65.0 °C(Predicted)
Density 
1.147
storage temp. 
2-8°C(protect from light)
pka
2.98±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
pal-Lys-Thr-Thr-Lys-Ser-OH
InChIKey
WSGCRSMLXFHGRM-DEVHWETNSA-N
SMILES
C(O)(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCCCC
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
5022AF
Product name
MatrixylAcetate(PalmitoyPentapeptide)
Packaging
250mg
Price
$309
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000055
Product name
PALMITOYL PENTAPEPTIDE-4
Purity
95.00%
Packaging
5MG
Price
$502.07
Updated
2021/12/16
AK Scientific
Product number
5022AF
Product name
MatrixylAcetate(PalmitoyPentapeptide)
Packaging
5g
Price
$3069
Updated
2021/12/16
Chemenu
Product number
CM251337
Product name
(2S,5S,8S,11S,14S)-5,14-Bis(4-aminobutyl)-8,11-bis((R)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oicacid
Purity
95%
Packaging
1g
Price
$449
Updated
2021/12/16
Crysdot
Product number
CD22003934
Product name
(2S,5S,8S,11S,14S)-5,14-Bis(4-aminobutyl)-8,11-bis((R)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oicacid
Purity
95+%
Packaging
1g
Price
$475
Updated
2021/12/16
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Palmitoyl Pentapeptide Chemical Properties,Usage,Production

Description

Palmitoyl pentapeptide-4 (formerly called palmitoyl pentapeptide-3) was the fi rst big successful breakthrough peptide ingredient and probably the most commonly used peptide for aging skin. Also known as Matrixyl?, palmitoyl pentatpeptide-4 has been demonstrated to signifi cantly increase collagen synthesis, improving the appearance of wrinkles and sagging of the aging skin. Palmitoyl pentapeptide-4 is basically a sequential piece of a collagen molecule. It is theorized to work by “tricking” the skin into “believing” that too much collagen has been broken down, thereby curbing the production of collagenase, the enzyme that destroys collagen, and stimulating fi broblasts, the cells that produce collagen. The results of using palmitoyl pentapeptide-4 are remarkable, and the performance ingredient does not cause the irritation that can be caused by other antiaging ingredients such as retinol.

Uses

palmitoyl pentapeptide-4 is a skin conditioner. Clinical studies by manufacturers credit it with an ability to promote collagen, elastin, and glycosaminoglycan synthesis. This would result in an ability to restore skin thickness, which diminishes with age, and to reduce the appearance of lines and wrinkles. Palmitoyl pentapeptide4 is a synthetic peptide with serine, threonine, and hexa decanoyl derivatives.
palmitoyl tetrapeptide-7 is formerly known as palmitoyl tetrapeptide3. This peptide appears to improve skin elasticity and firmness. It also hydrates, smoothes, and protects the skin. It can be both obtained from the plant and synthetically derived and is found in a variety of different skin care preparations including eye lotions, moisturizers, and night creams. Palmitoyl tetrapeptide3 appears to act as an anti-inflammatory. This is attributed to its ability to control the secretion of specific chemicals responsible for skin aging (i.e., cytokines and interleukin-6), and hence it may function in a manner similar to the anti-aging hormone, DHeA. Some studies indicate that palmitoyl tetrapeptide-7 may also act as a uV filter.

Uses

Myristoyl pentapeptide-4 is polypeptide used in masks for skin and muscles of face. Also, used in anti-wrinkle and firming facial cleanser.

Definition

palmitoyl pentapeptide-4 is a skin conditioner. Clinical studies by manufacturers credit it with an ability to promote collagen, elastin, and glycosaminoglycan synthesis. This would result in an ability to restore skin thickness, which diminishes with age, and to reduce the appearance of lines and wrinkles. Palmitoyl pentapeptide-4 is a synthetic peptide with serine, threonine, and hexadecanoyl derivatives.

benefits

Palmitoyl Pentapeptide-4 is effectivly reduce various kind of facial wrinkles;Replenish the collagen and polysaccharide, repairthe skin.Winkey patented productin China.It is recommended dosage is 3~10%.

benefits

Palmitoyl pentapeptide-4 was the first peptide to be widely used in products for aging skin. It stimulates collagen and reduces the production of collagenase, the enzyme that breaks down collagen in photoaging skin.
Palmitoyl pentapeptide-4 boost tissue regeneration, activate production of collagen, sucrose osamine and hyaluronic acid,widely used on the long-lasting aging formula. Its recommended dosage is 3~8%.

Mechanism of action

Palmitoyl Pentapeptide appears to work by increasing collagen production, stimulating collagen, elastin, and hyaluronic acid growth, increasing the skin's moisture content and retention, which helps reduce the appearance of fine lines and wrinkles on the skin's surface. Pentapeptide is equivalent to intimate integration with the skin, changing the skin ecology and cell repair, and playing the role of intracellular hormones and enzymes.

Properties and Applications

Cosmetic polypeptides can penetrate the dermis to increase the level of collagen and reverse the aging process of the skin through rebuilding from inside to outside.
Cosmetic pentapeptide(Palmitoyl Pentapeptide) is also a cosmetic polypeptide. The prototype of the polypeptide is palmitic acid pentapeptide, commonly known as the five peptides, being able to simulate the paralysis effect of botulinum toxin. It is a short peptide fragment consisting of five amino acids formed by peptide bonds with its structure being similar to the protein. However, the protein has a longer peptide chain, usually consisting of hundreds of amino acids. Based on the differences of the number of amino acids, these polypeptides are divided into dipeptides (including two amino acids), tripeptides (including three amino acids), tetrapeptides (including four amino acids), etc. Because of the different categories of amino acids contained, both dipeptides and tripeptides have different varieties. At the same time, even with the same number of amino acids, the dipeptides will still have different varieties due to the different sort order of the amino acid. This leads to a number of peptides with a variety of roles and names. The pentapeptide is composed of six amino acids (Pal palmitic acid, Lys-lysine, Thr-threonine, Thr-threonine, Lys-lysine and Ser-serine).
The Palmitoyl Pentapeptide is actually the C-terminal fragment of Collagen I, having an effect being similar to that of the laser surgery. It can stimulate the growth of collagen, stretch fibers and hyaluronic acid, improve skin moisture and the degree of locking water, increase skin thickness and reduce the microgroove; at the same time, addition of a long chain of fatty acids (palmitic acid) can increase the absorption effect. Compared with the laser surgery, the five-peptides is equivalent to intimate fusion with the skin, changing the skin ecology and cell repair, further playing the role of intracellular hormones and enzymes.

Palmitoyl Pentapeptide Preparation Products And Raw materials

Raw materials

Preparation Products

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Palmitoyl Pentapeptide Suppliers

Lavem Chine Pharm Company
Tel
28-86066080 18280039962
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86-28-8527-5264
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sales@lavemc.com
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China
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214
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Nanjing Leon Biological Technology Co., Ltd.
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17705183659
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84523390
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sales@njleonbiotech.com
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China
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5501
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Chengdu Youngshe Chemical Co., Ltd.
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+86-17380623303 +86-17380623303
Fax
028-62328193
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Caroline@youngshechem.com
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China
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4803
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Spec-Chem Industry Inc.
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025-84523390 13505162978
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sc@specchemind.com
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China
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117
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Nanjing Yuanpeptide Biotech Co.,Ltd.
Tel
18168071971
Email
support@yuan-peptide.com
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China
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2983
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Chengdu Shengnuo Biological Peptide Technology Co.,Ltd
Tel
028-88368562
Email
liweidan@snbiopharm.com
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China
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27
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58
Shandong Jitai Biotech Co., Ltd
Tel
18366132549
Email
372278065@qq.com
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China
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30
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58
Zhangzhou Sinobioway Peptide Co. Ltd.
Tel
18750546777
Email
SINOPEPT@GMAIL.COM
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China
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6093
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Alabiochem Tech.Co., Ltd.
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512-58900862 400-0707518
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0086-512-56765862
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sales@alabiochem.com
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Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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GL Biochem (Shanghai) Ltd
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21-61263452 13641803416
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86-21-61263399
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ymbetter@glbiochem.com
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Nanjing Search Biotech Co., Ltd
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sales@searchbio.com.cn
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137
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
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info@hanhongsci.com
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
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ivy@hnhbsj.com
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Cellmano Biotech Limited
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0551-65326643 18156095617
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0551-65326641
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ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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021-55068248
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shyysw007@163.com
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Beijing HuaMeiHuLiBiological Chemical
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010-56205725
Fax
010-65763397
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waley188@sohu.com
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12335
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Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
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sales@sunlidabio.com
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China
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3239
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TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
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marketing@targetmol.com
Country
China
ProdList
7783
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58
Shifang ShengYuan Technology Co., Ltd.
Tel
028-0838-6510595 13402890778 13402890778
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1120021438@qq.com
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132
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ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
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sales@chem-strong.com
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China
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18110
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Shenzhen JYMed Technology Co., Ltd.
Tel
755-755-26612112 15013529272;
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+86 (755) 8635-0488
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jymed@jymedtech.com
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China
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81
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
Fax
051085625359
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sales@reading-chemicals.com
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China
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15178
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Shaanxi Pioneer Biotech Co., Ltd.
Tel
13720616393;029-84385017-8003 13720616393
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029-84385017
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sales@pioneerbiotech.com
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China
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778
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NINGBO INNO PHARMCHEM CO.,LTD.
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86-574-27787657
Fax
86-574-27912196
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info@dearchem.com
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China
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4613
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58
Shanghai HuanChuan Industry Co.,Ltd.
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021-61478794
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021-61478794
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sales@hcshhai.com
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China
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9793
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50
Credit Asia Chemical Co., Ltd.
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+86 (21) 61124340
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+86 (21) 6129-4103
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9756
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58
Hubei Jusheng Technology Co.,Ltd
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027-59599241 18871490274
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027-59599241
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1400878000@qq.com
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China
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9959
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Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
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xg01_gj@163.com
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China
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50
Watson Biotechnology Co.,Ltd
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027-59207879 1972026995 18140587686
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QQ:1972026995
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Kono Chem Co.,Ltd
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15829389671
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029-86107037
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412
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Shanghai Synchem Pharma Co., ltd
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21-619849051-1 18521059765
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synchempharma@aliyun.com
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6468
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Shanghai Send Pharmaceutical Technology Co., Ltd.
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021-58088081 Q3252066219
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QQ3382968513
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Avantpbc Chemical Tech(Shanghai) Co,Ltd.
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17802107445
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China
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Shanghai QianYan Bio-technology Co., Ltd
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02781293128
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orders@biochemsafebuy.com
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Lancrix Chemicals
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86-21-50817262
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86-21-57712035
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Raw material medicin reagent co.,Ltd
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Shanghai Chaolan Chemical Technology Center
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021-QQ:65489617 15618227136
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21-5161 9052
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Wuxi Asia Peptide Biotechnology Limited Company
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0510-83583050 13771062561
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0510-83583039
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willsun@peptide-search.com
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China
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6716
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Shenzhen Simeiquan Biotechnology Co. Ltd
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18126413629 0755-23311925 2355327053
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0755-23311925
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abel@ycgmp.com
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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Shenzhen Sendi Biological Technology Co., Ltd.
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18124570582 TEL:0755-23574479 2355327139
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0755-23229476 QQ: 2355327139
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siliao02@yccreate.com
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Anhui kuer Bioengineering Co., Ltd
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0551-65171243 13856024262
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kuer@kuerhuaxue.com
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2992
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Guangzhou Kafen Biotech Co.,Ltd
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18029243487 2355327168
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020-31121510
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gy@yccreate.com
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4749
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Nanjing Peptide Biotech Ltd.
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025-025-58361106-805-805 13082558573
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025-58361106-806
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liugang@njpeptide.com
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China
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9980
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Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.
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027-65526929 15102793023
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027-65526669
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hbhxry@foxmail.com
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Wellman Pharmaceutical Group Limited
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027-83778875 15807197853
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027-83991220
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Shanghai Orgchem Co.,Ltd.
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+86-21-5877 1921
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+86-21-5877 1925
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info@chemofchina.com
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Amatek Scientific Co. Ltd.
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0512-56316828
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0512-56316826
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Alpha Biopharmaceuticals Co., Ltd
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+86-15542445688
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0086-411-39042693
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sales@alphabiopharm.com
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China
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View Lastest Price from Palmitoyl Pentapeptide manufacturers

Forest chemical technology
Product
Palmitoyl Pentapeptide 214047-00-4
Price
US $0.00-0.00/G
Min. Order
1G
Purity
99%
Supply Ability
1 ton/year
Release date
2025-02-15
Shenzhen Aoxi Technology Co., Ltd.
Product
Matrixyl 214047-00-4
Price
US $30.00-10.00/kit
Min. Order
1kit
Purity
99%
Supply Ability
10000kits
Release date
2025-03-19
Wuhan Haorong Biotechnology Co.,Ltd
Product
PTD-DBM 214047-00-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500
Release date
2023-07-17

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