BENAZEPRIL HCL

Product Name
BENAZEPRIL HCL
CAS No.
3202-55-9
Chemical Name
BENAZEPRIL HCL
Synonyms
ap1288;brl1288;Benapryzine HCl;benapryzinehydrochloride;Benaprizine Hydrochloride;benzilicacid,2-(ethylpropylamino)ethylester,hydrochloride;alpha-hydroxy-alpha-phenyl-benzeneaceticaci2-(ethylpropylamino)ethyles
CBNumber
CB5122019
Molecular Formula
C24H29ClN2O5
Formula Weight
460.95
MOL File
3202-55-9.mol
More
Less

BENAZEPRIL HCL Property

Melting point:
164-166°
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0016041
Product name
BENAPRYZINE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$504.01
Updated
2021/12/16
More
Less

BENAZEPRIL HCL Chemical Properties,Usage,Production

Originator

Brizin,Beecham,UK,1973

Uses

Anticholinergic.

Manufacturing Process

A methanolic solution of sodium methoxide [from sodium (0.2 gram) and dry methanol (3 ml)] was added dropwise during 20 minutes to a boiling solution of methyl α,α-diphenylglycollate (11 grams) and 2-ethylpropylaminoethanol (6 grams) in light petroleum (150 ml, BP 80°-100°C) and the methanol that separated was removed by using a Dean and Starke apparatus. At the end of 5 hours no further separation of methanol occurred and the reaction mixture after being washed with water (3 x 20 ml) was extracted with 1N hydrochloric acid (3 x 30 ml).
The acid extracts (after washing with 50 ml ether) were made alkaline with aqueous 5 N sodium hydroxide solution, the liberated base was extracted into ether (4 x 50 ml) and the ether extracts were dried (MgSO4). Treatment of the extracts with hydrogen chloride gave the hydrochloride (11 grams, 70%), which was obtained as rectangular plates, MP 164° to 166°C, after several crystallizations from butanone.

Therapeutic Function

Anticholinergic, Antiparkinsonian

BENAZEPRIL HCL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BENAZEPRIL HCL Suppliers

3202-55-9, BENAZEPRIL HCLRelated Search:


  • alpha-hydroxy-alpha-phenyl-benzeneaceticaci2-(ethylpropylamino)ethyles
  • ap1288
  • benapryzinehydrochloride
  • benzilicacid,2-(ethylpropylamino)ethylester,hydrochloride
  • brl1288
  • Benapryzine HCl
  • Benaprizine Hydrochloride
  • 3202-55-9