2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt

Product Name: 2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt
CAS No.: 73606-19-6
Chemical Name: 2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt
Synonyms: Potassium 9-Chlorohexadecafluoro-3-Oxanonane-1-Sulfonate;RMA-730;6:2 Cl-PFAES;C8 Cl-PFESA Potassium Salt;9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid potassium;9-Chlorohexadecafluoro-3-oxanone-1-sulfonic Acid (potassium salt);Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate in Methanol;Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate in Acetonitrile;9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid potassium 50 μg/mL in Methanol:Water;Potassium 9-chlorohexadecafluoro-3-oxanone-1-sulfonate (9Cl-PF3ONS) (F53B Major) (unlabeled)
CBNumber: CB51234555
Molecular Formula: C8H2ClF16KO4S
Formula Weight: 572.68
MOL File: 73606-19-6.mol

More

Less

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Property

storage temp.: 2-8°C
solubility: DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml
InChI: InChI=1S/C8HClF16O4S.K.H/c9-5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)29-7(22,23)8(24,25)30(26,27)28;;/h(H,26,27,28);;
InChIKey: LPOJQHZZFKUHOD-UHFFFAOYSA-N
SMILES: C(F)(F)(C(F)(F)C(F)(F)C(F)(F)Cl)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)S(O)(=O)=O.[KH]
EPA Substance Registry System: Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate (73606-19-6)

More

Less

Safety

WGK Germany: WGK 3
Storage Class: 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications: Acute Tox. 3 Oral
Acute Tox. 4 Inhalation
Aquatic Chronic 2
Carc. 2
Lact.
Repr. 1B
STOT RE 1

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H332Harmful if inhaled

H351Suspected of causing cancer

H362May cause harm to breast-fed children

H372Causes damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More

Less

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Chemical Properties,Usage,Production

Description

9-Chlorohexadecafluoro-3-oxanone-1-sulfonic acid (9Cl-PF3ONS) is a chlorinated polyfluoroalkyl substance (PFAS).1 It binds to the ligand-binding domains of estrogen receptor α (ERα) and ERβ (IC50s = 99.3 and 63.4 µM, respectively, for the human receptors) and increases the levels of vitellogenin (Vtg), estradiol (E2), and testosterone in zebrafish larvae when used at a concentration of 500 nM. 9Cl-PF3ONS (20 and 100 mg/kg) decreases serum triiodothyronine (T3) and thyroxine (T4) levels and induces thyroid gland follicular hyperplasia in rats.2 It has been found in breast milk and negatively correlates with infant length gain rate.3 9Cl-PF3ONS has also been found in river and lake water.4WARNING This product is not for human or veterinary use.

Health effects

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt can induce oxidative stress by damaging the body's antioxidant system.

References

[1] YAN XIN. Chlorinated Polyfluoroalkylether Sulfonic Acids Exhibit Stronger Estrogenic Effects than Perfluorooctane Sulfonate by Activating Nuclear Estrogen Receptor Pathways[J]. Environmental Science and Technology, 2020, 54 6: 3455-3464. DOI: 10.1021/acs.est.9b07708
[2] SO-HYE HONG. Orally Administered 6:2 Chlorinated Polyfluorinated Ether Sulfonate (F-53B) Causes Thyroid Dysfunction in Rats.[J]. Toxics, 2020. DOI: 10.3390/toxics8030054
[3] HANGBIAO JIN . Poly- and perfluoroalkyl substance concentrations in human breast milk and their associations with postnatal infant growth[J]. Science of the Total Environment, 2020, 713: Article 136417. DOI: 10.1016/j.scitotenv.2019.136417
[4] YUAN WANG; Yaqi C; Yali Shi. Spatial distribution, seasonal variation and risks of legacy and emerging per- and polyfluoroalkyl substances in urban surface water in Beijing, China[J]. Science of the Total Environment, 2019, 673: Pages 177-183. DOI: 10.1016/j.scitotenv.2019.04.067

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Suppliers

China 46 Germany 1 Ukraine 1 United Kingdom 1 United States 2 Global 51

Shanghai Meiquan Chemical Technology Co., Ltd.

Tel: 15802146997; 15802146997
Email: zkq1984@163.com
Country: China
ProdList: 468
Advantage: 58

Suzhou Haiben Pharmaceutical Co., Ltd

Tel: 19353112242
Email: 1816280386@qq.com
Country: China
ProdList: 8045
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39999
Advantage: 60

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15781
Advantage: 55

Alfa Chemistry

Tel: 1-516-6625404
Fax: 1-516-927-0118
Email: support@alfa-chemistry.com
Country: United States
ProdList: 9171
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8615838112936
Email: sale03@alfachem.cn
Country: China
ProdList: 9659
Advantage: 58

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

More

Less

View Lastest Price from 2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt manufacturers

Career Henan Chemical Co

Product: 2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt 73606-19-6
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

73606-19-6, 2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium saltRelated Search:

Permethrin

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt

2-[(6-Chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy]-1,1,2,2-tetrafluoroethanesulfonic acid potassium salt

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt ISO 9001：2015 REACH

Potassium 9-Chlorohexadecafluoro-3-Oxanonane-1-Sulfonate

2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonicacid,potassiumsal

Potassium 2-((6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy)-1,1,2,2-tetrafluoroethanesulfonate

9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid potassium 50 μg/mL in Methanol:Water

9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid potassium

Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate in Methanol

Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate in Acetonitrile

6:2 Cl-PFAES

9-Chlorohexadecafluoro-3-oxanone-1-sulfonic Acid (potassium salt)

Potassium 9-chlorohexadecafluoro-3-oxanone-1-sulfonate (9Cl-PF3ONS) (F53B Major) (unlabeled)

Potassium 2-((6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy)-1,1,2,2-tetrafluoroethane-1-sulfonate

RMA-730

C8 Cl-PFESA Potassium Salt

73606-19-6

C8HClF16O4SK