1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI)
- Product Name
- 1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI)
- CAS No.
- 126674-95-1
- Chemical Name
- 1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI)
- Synonyms
- 5-methoxy-2-methylpyrazole-3-carboxylic Acid;1-Methyl-3-methoxypyrazole-5-carboxylic acid;3-Methoxy-1-Methyl-1H-pyrazole-5-carboxylic acid;1H-PYRAZOLE-5-CARBOXYLIC ACID, 3-METHOXY-1-METHYL-;1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI)
- CBNumber
- CB51285805
- Molecular Formula
- C6H8N2O3
- Formula Weight
- 156.14
- MOL File
- 126674-95-1.mol
1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI) Property
- Boiling point:
- 343.4±22.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 2.90±0.25(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M336283
- Product name
- 3-Methoxy-1-methyl-1H-pyrazole-5-carboxylicacid
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 7031DF
- Product name
- 3-Methoxy-1-methyl-1H-pyrazole-5-carboxylicacid
- Packaging
- 100mg
- Price
- $157
- Updated
- 2021/12/16
- Product number
- CHM0389234
- Product name
- 3-METHOXY-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495
- Updated
- 2021/12/16
- Product number
- A121636
- Product name
- 3-Methoxy-1-methyl-1H-pyrazole-5-carboxylicacid
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $94
- Updated
- 2021/12/16
- Product number
- A121636
- Product name
- 3-Methoxy-1-methyl-1H-pyrazole-5-carboxylicacid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $94
- Updated
- 2021/12/16
1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI) Chemical Properties,Usage,Production
Synthesis
55781-86-7
126674-95-1
The general procedure for the synthesis of 3-methoxy-1-methyl-1H-pyrazole-5-carboxylic acid from methyl 3-methoxy-1-methyl-1H-pyrazole-5-carboxylate was as follows: to a solution of methanol (5 mL) containing methyl 3-methoxy-1-methyl-1H-pyrazole-5-carboxylate (220.7 mg, 1.30 mmol) was added 1 M aqueous sodium hydroxide (1.30 mL, 1.30 mmol). The reaction mixture was stirred at room temperature for 5 hours. Upon completion of the reaction, the methanol was removed by concentration under reduced pressure, and the pH was adjusted to acidic with 1 M hydrochloric acid solution, followed by extraction with ethyl acetate (3 × 10 mL). The organic layers were combined, washed with saturated aqueous sodium chloride solution (10 mL) and dried over anhydrous magnesium sulfate. After filtration, the filtrate was concentrated under reduced pressure to give the title compound 3-methoxy-1-methyl-1H-pyrazole-5-carboxylic acid (163 mg, 80% yield) as a white solid. Mass spectrum (ESI-): m/z 155 [M-H]-. 1H NMR (300 MHz, DMSO-d6) δ 3.77 (3H, s), 3.92 (3H, s), 6.20 (1H, s), 13.38 (1H, br s).
References
[1] Patent: EP2530078, 2012, A1. Location in patent: Page/Page column 209-210
[2] Patent: US2009/137595, 2009, A1
1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI) manufacturers
- Product
- 1H-Pyrazole-5-carboxylicacid,3-methoxy-1-methyl-(9CI) 126674-95-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kf/month
- Release date
- 2019-12-10