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3-(TRIFLUOROACETYL)INDOLE

Product Name
3-(TRIFLUOROACETYL)INDOLE
CAS No.
14618-45-2
Chemical Name
3-(TRIFLUOROACETYL)INDOLE
Synonyms
3-(TRIFLUOROACETYL)INDOLE;3-(TRIFLUOROACETYL)INDOLE 99%;3-Indolyl trifluoromethyl ketone;Ethanone, 2,2,2-trifluoro-1-(1H-indol-3-yl)-;2,2,2-TRIFLUORO-1-(1H-INDOL-3-YL)-1-ETHANONE
CBNumber
CB5129548
Molecular Formula
C10H6F3NO
Formula Weight
213.16
MOL File
14618-45-2.mol
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3-(TRIFLUOROACETYL)INDOLE Property

Melting point:
211-214 °C(lit.)
Boiling point:
308.6±37.0 °C(Predicted)
Density 
1.423±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
Solid
pka
14.31±0.30(Predicted)
color 
White to Almost white
CAS DataBase Reference
14618-45-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933992000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T1809
Product name
3-(Trifluoroacetyl)indole
Purity
>98.0%(GC)
Packaging
1g
Price
$54
Updated
2024/03/01
TCI Chemical
Product number
T1809
Product name
3-(Trifluoroacetyl)indole
Purity
>98.0%(GC)
Packaging
5g
Price
$154
Updated
2024/03/01
Alfa Aesar
Product number
H66000
Product name
3-(Trifluoroacetyl)indole, 97%
Packaging
1g
Price
$43.5
Updated
2023/06/20
Alfa Aesar
Product number
H66000
Product name
3-(Trifluoroacetyl)indole, 97%
Packaging
5g
Price
$193
Updated
2023/06/20
TRC
Product number
T793693
Product name
3-(Trifluoroacetyl)indole
Packaging
100mg
Price
$75
Updated
2021/12/16
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3-(TRIFLUOROACETYL)INDOLE Chemical Properties,Usage,Production

Uses

Reactant for enantioselective synthesis of indoles via palladium-catalyzed kinetic asymmetrical alkylation. Reactant for preparation of N-pyridinyl indolecarboxamides via amidation of aminopyridine derivatives. with indolecarboxylic acid 2 Reactant for preparation of mast cell tryptase inhibitors, starting from indoles; using amidation as the key step 3 Reactant for formation of Michael adducts via Baylis-Hillman reaction 4 Reactant for preparation of indolecarboxamides via haloform cleavage of (trifluoroacetyl)indole with lithium dialkylamides.

Uses

  • Reactant for enantioselective synthesis of indoles via palladium-catalyzed kinetic asymmetrical alkylation
  • Reactant for preparation of N-pyridinyl indolecarboxamides via amidation of aminopyridine derivatives. with indolecarboxylic acid
  • Reactant for preparation of mast cell tryptase inhibitors, starting from indoles; using amidation as the key step
  • Reactant for formation of Michael adducts via Baylis-Hillman reaction
  • Reactant for preparation of indolecarboxamides via haloform cleavage of (trifluoroacetyl)indole with lithium dialkylamides

General Description

3-(Trifluoroacetyl)indole is a heterocyclic trifluoromethyl ketone. One of the methods reported for its synthesis is by the reaction of indole with trifluoroacetic anhydride.

3-(TRIFLUOROACETYL)INDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(TRIFLUOROACETYL)INDOLE Suppliers

Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63711
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
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View Lastest Price from 3-(TRIFLUOROACETYL)INDOLE manufacturers

Career Henan Chemical Co
Product
3-(TRIFLUOROACETYL)INDOLE 14618-45-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-24

14618-45-2, 3-(TRIFLUOROACETYL)INDOLERelated Search:


  • 2,2,2-TRIFLUORO-1-(1H-INDOL-3-YL)-1-ETHANONE
  • 3-(TRIFLUOROACETYL)INDOLE
  • 3-(TRIFLUOROACETYL)INDOLE 99%
  • 3-Indolyl trifluoromethyl ketone
  • Ethanone, 2,2,2-trifluoro-1-(1H-indol-3-yl)-
  • 14618-45-2
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