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N-succinimidyl-4-((iodoacetyl)amino)benzoate

Product Name
N-succinimidyl-4-((iodoacetyl)amino)benzoate
CAS No.
72252-96-1
Chemical Name
N-succinimidyl-4-((iodoacetyl)amino)benzoate
Synonyms
N-succinimidyl-(4-iodoacetamido)benzoate;2-(2,5-dioxopyrrolidin-1-yl)-4-[(iodoacetyl)amino]benzoate;4-[(2-Iodoacetyl)aMino]benzoic Acid 2,5-dioxo-1-pyrrolidinyl Ester;N-[4-[[(2,5-Dioxopyrrolidin-1-yl)oxy]carbonyl]phenyl]-2-iodoacetamide;Benzoic acid, 4-[(2-iodoacetyl)amino]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB51309949
Molecular Formula
C13H11IN2O5
Formula Weight
402.14
MOL File
72252-96-1.mol
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N-succinimidyl-4-((iodoacetyl)amino)benzoate Property

Melting point:
19-7-200°C (dec.)
Density 
1.87±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Acetontrile (Slightly), DMSO (Slightly)
form 
Solid
pka
12.16±0.70(Predicted)
color 
Pale Yellow
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Safety

HS Code 
2921490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
803669
Product name
SIAB (N-succinimidyl (4-iodoacetyl)aminobenzoate)
Packaging
50MG
Price
$375
Updated
2022/05/15
TRC
Product number
S690300
Product name
N-Succinimidyl(4-Iodoacetyl)aminobenzoate
Packaging
25mg
Price
$80
Updated
2021/12/16
TRC
Product number
S690300
Product name
N-Succinimidyl(4-Iodoacetyl)aminobenzoate
Packaging
50mg
Price
$140
Updated
2021/12/16
AK Scientific
Product number
7579AH
Product name
N-Succinimidyl(4-iodoacetyl)aminobenzoate
Packaging
100mg
Price
$131
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0009029
Product name
N-SUCCINIMIDYL (4-IODOACETYL)AMINOBENZOATE
Purity
95.00%
Packaging
100MG
Price
$686.65
Updated
2021/12/16
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N-succinimidyl-4-((iodoacetyl)amino)benzoate Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 10.6 Angstroms

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 10.6 Angstroms

General Description

SIAB is an amine- and sulfhydryl-reactive heterobifunctional crosslinker and Sulfo-SIAB is its water-soluble analog. These crosslinkers contain an amine-reactive N-hydroxysuccimide (NHS) ester and a sulfhydryl-reactive iodoacetyl group, and are often used for preparing enzyme conjugates or immunotoxins. Water-soluble and water-insoluble forms of NHS esters have essentially identical reactivity. Sulfo-SIAB is supplied as a sodium salt and is water-soluble to ~10mM. SIAB must be first dissolved in an organic solvent, such as DMSO or DMF, and then added to the aqueous reaction mixture. SIAB is lipophilic, membrane-permeable and does not possess a charged group.

N-succinimidyl-4-((iodoacetyl)amino)benzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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N-succinimidyl-4-((iodoacetyl)amino)benzoate Suppliers

72252-96-1, N-succinimidyl-4-((iodoacetyl)amino)benzoateRelated Search:


  • N-succinimidyl-(4-iodoacetamido)benzoate
  • 4-[(2-Iodoacetyl)aMino]benzoic Acid 2,5-dioxo-1-pyrrolidinyl Ester
  • N-[4-[[(2,5-Dioxopyrrolidin-1-yl)oxy]carbonyl]phenyl]-2-iodoacetamide
  • Benzoic acid, 4-[(2-iodoacetyl)amino]-, 2,5-dioxo-1-pyrrolidinyl ester
  • 2-(2,5-dioxopyrrolidin-1-yl)-4-[(iodoacetyl)amino]benzoate
  • 72252-96-1
  • C13H11IN2O5
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents