ChemicalBook > CAS DataBase List > PL017

PL017

Product Name
PL017
CAS No.
83397-56-2
Chemical Name
PL017
Synonyms
PL017;TYR-PRO-(NME)PHE-DPRO-NH2;morphiceptin, N-Me-Phe(3)-;[NMPhe3,D-Pro4]morphiceptin;H-TYR-PRO-N-ME-PHE-D-PRO-NH2;[N-ME-PHE3, D-PRO4]-MORPHICEPTIN;L-Tyr-L-Pro-N-Methyl-L-Phe-D-Pro-NH2;[(NME)PHE3, DPRO4] MORPHICEPTIN, BOVINE;[NMePhe3, DPro4] b-Casomorphin: 1-4, amide, bovine;{N-METHYL-PHE3,D-PRO4}-BETA-CASOMORPHIN FRAGMENT 1-
CBNumber
CB5131318
Molecular Formula
C29H37N5O5
Formula Weight
535.63
MOL File
83397-56-2.mol
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PL017 Property

Boiling point:
878.5±65.0 °C(Predicted)
Density 
1.313±0.06 g/cm3(Predicted)
storage temp. 
−20°C
form 
Powder
pka
9.86±0.15(Predicted)
Water Solubility 
Soluble to 1 mg/ml in water
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
256279
Product name
PL 017
Packaging
1mg
Price
$296
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000669
Product name
PL017
Purity
95.00%
Packaging
5MG
Price
$755.95
Updated
2021/12/16
ApexBio Technology
Product number
B5249
Product name
PL017
Packaging
1mg
Price
$108
Updated
2021/12/16
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PL017 Chemical Properties,Usage,Production

Biological Activity

PL-017 is a potent and selective μ opioid receptor agonist with IC50 of 5.5 nM for 125I-FK 33,824 binding to the μ site. PL-017 produces durable and reversible analgesia in rats.

in vitro

PL-017 has an IC 50 of 10000 nM for 125 I-DADLE binding to δ site.

in vivo

PL-017 (0.22, 0.45, 0.9 nmol/rat; icv) has the time of maximum effect of approximately 15 to 30 mm after injection at lower doses and produces analgesia lasting as long as 4 hours with larger doses in male Sprague-Dawley rats weighing 250 to 375 g.

target

IC50: 5.5 nM ( 125 I-FK 33,824 binding to μ site)

PL017 Preparation Products And Raw materials

Raw materials

Preparation Products

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PL017 Suppliers

GL Biochem (Shanghai) Ltd
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View Lastest Price from PL017 manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(N-Me-Phe3,D-Pro4)-β-Casomorphin (1-4) amide (bovine) 83397-56-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-10

83397-56-2, PL017Related Search:


  • (N-ME-PHE3,D-PRO4)-BETA-CASOMORPHIN (1-4) AMIDE (BOVINE)
  • [N-ME-PHE3, D-PRO4]-MORPHICEPTIN
  • [(NME)PHE3, DPRO4] MORPHICEPTIN, BOVINE
  • PL017
  • TYR-PRO-(NME)PHE-DPRO-NH2
  • H-TYR-PRO-N-ME-PHE-D-PRO-NH2
  • {N-METHYL-PHE3,D-PRO4}-BETA-CASOMORPHIN FRAGMENT 1-
  • [n-methyl-phe3, d-pro4]-β-casomorphin fragment 1-4 amide, bovine
  • morphiceptin, N-Me-Phe(3)-
  • [NMPhe3,D-Pro4]morphiceptin
  • L-Tyr-L-Pro-N-Methyl-L-Phe-D-Pro-NH2
  • [NMePhe3, DPro4] b-Casomorphin: 1-4, amide, bovine
  • (N-Me-Phe3,D-Pro4)-β-Casomorphin (1-4) amide (bovine)
  • D-Prolinamide, L-tyrosyl-L-prolyl-N-methyl-L-phenylalanyl-
  • 83397-56-2
  • C29H37N5O5
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