ChemicalBook > CAS DataBase List > glycyl-arginyl-glycyl-aspartyl-seryl-proline

glycyl-arginyl-glycyl-aspartyl-seryl-proline

Product Name: glycyl-arginyl-glycyl-aspartyl-seryl-proline
CAS No.: 91037-75-1
Chemical Name: glycyl-arginyl-glycyl-aspartyl-seryl-proline
Synonyms: glycyl-arginyl-glycyl-aspartyl-seryl-proline;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline;L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-
CBNumber: CB51329233
Molecular Formula: C22H37N9O10
Formula Weight: 587.58
MOL File: 91037-75-1.mol

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glycyl-arginyl-glycyl-aspartyl-seryl-proline Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white
Sequence: Gly-Arg-Gly-Asp-Ser-Pro

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7039
Product name: GRGDSP
Packaging: 5mg
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-7039
Product name: GRGDSP
Packaging: 10mg
Price: $290
Updated: 2021/12/16

ChemScene

Product number: CS-7039
Product name: GRGDSP
Packaging: 25mg
Price: $640
Updated: 2021/12/16

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glycyl-arginyl-glycyl-aspartyl-seryl-proline Chemical Properties,Usage,Production

Uses

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

Biological Activity

GRGDSP is a synthetic linear RGD peptide that is an integrin inhibitor.

in vitro

It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly -Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.

target

Integrin

References

[1] Qian J, et al. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model. World J Gastroenterol. 2016 Jun 7;22(21):5042-9. DOI:10.3748/wjg.v22.i21.5042
[2] Patel S, et al. Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers. J Biomed Mater Res A. 2007 Nov;83(2):423-33. DOI:10.1002/jbm.a.31320

glycyl-arginyl-glycyl-aspartyl-seryl-proline Preparation Products And Raw materials

Raw materials

Preparation Products

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91037-75-1, glycyl-arginyl-glycyl-aspartyl-seryl-prolineRelated Search:

glycyl-arginyl-glycyl-aspartyl-seryl-proline

Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline

L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-

91037-75-1