althiomycin

Product Name: althiomycin
CAS No.: 12656-40-5
Chemical Name: althiomycin
Synonyms: 116-A;Matamycin;NS-102809;Nsc 102809;althiomycin;N-[1-[4-[(2,5-Dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl]-4,5-dihydrothiazol-2-yl]-2-hydroxyethyl]-2-[(hydroxyimino)methyl]-4-thiazolecarboxamide;4-Thiazolecarboxamide, N-[1-[(4S)-4-[(2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl]-4,5-dihydro-2-thiazolyl]-2-hydroxyethyl]-2-[(E)-(hydroxyimino)methyl]-
CBNumber: CB51332378
Molecular Formula: C16H17N5O6S2
Formula Weight: 439.47
MOL File: 12656-40-5.mol

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althiomycin Property

Melting point:: 172-174 °C (decomp)
Density: 1.72±0.1 g/cm3(Predicted)
storage temp.: -20°C
pka: 9.67±0.10(Predicted)
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

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althiomycin Chemical Properties,Usage,Production

Uses

Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 μg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 μg/mL but not in isolated rabbit reticulocytes at 100 μg/mL.

References

[1] Gerc, et al. The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin. PLoS One 7(9), e44673 (2012).

althiomycin Preparation Products And Raw materials

Raw materials

Preparation Products

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althiomycin Suppliers

China 10 South Korea 1 United States 3 Global 14

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
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TargetMol Chemicals Inc.

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BOC Sciences

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Zhejiang Huida Biotech Co., LTD

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ChemeGen

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Zhejiang Huida Biotech Co., LTD

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InvivoChem

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TargetMol Chemicals Inc.

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Cayman Chemical Company

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Biosynth Biological Technology (Suzhou) Co Ltd

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12656-40-5, althiomycinRelated Search:

4-METHOXY-3-PYRROLIN-2-ONE 2-ethyl-4,5-dihydrothiazole althiomycin

althiomycin

N-[1-[4-[(2,5-Dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl]-4,5-dihydrothiazol-2-yl]-2-hydroxyethyl]-2-[(hydroxyimino)methyl]-4-thiazolecarboxamide

116-A

Matamycin

Nsc 102809

4-Thiazolecarboxamide, N-[1-[(4S)-4-[(2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl]-4,5-dihydro-2-thiazolyl]-2-hydroxyethyl]-2-[(E)-(hydroxyimino)methyl]-

NS-102809

12656-40-5

C16H17N5O6S2