scyliorhinin II

Product Name: scyliorhinin II
CAS No.: 112748-19-3
Chemical Name: scyliorhinin II
Synonyms: PubChem ID: 101569057;L-Methioninamide, L-seryl-L-prolyl-L-seryl-L-asparaginyl-L-seryl-L-lysyl-L-cysteinyl-L-prolyl-L-α-aspartylglycyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-valylglycyl-L-leucyl-, cyclic (7→13)-disulfide
CBNumber: CB51347972
Molecular Formula: C77H119N21O26S3
Formula Weight: 1851.09
MOL File: 112748-19-3.mol

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scyliorhinin II Property

Boiling point:: 2202.7±65.0 °C(Predicted)
Density: 1.47±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 4.01±0.10(Predicted)
Sequence: Ser-Pro-Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0045214
Product name: ScyliorhininII
Packaging: 1mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0045214
Product name: ScyliorhininII
Packaging: 5mg
Price: $260
Updated: 2021/12/16

ChemScene

Product number: CS-0045214
Product name: ScyliorhininII
Packaging: 10mg
Price: $420
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0009221
Product name: SCYLIORHININ II AMIDE-DOGFISH
Purity: 95.00%
Packaging: 1MG
Price: $641.03
Updated: 2021/12/16

ChemScene

Product number: CS-0045214
Product name: ScyliorhininII
Packaging: 25mg
Price: $840
Updated: 2021/12/16

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scyliorhinin II Chemical Properties,Usage,Production

Uses

Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.

in vivo

Scyliorhinin II produces potent, dose-related reciprocal hindlimb scratching about equipotently with an ED₅₀ of 0.08 nmol via intracerebroventricularly (i.c.v.) administration in mice^[2].

References

[1] Buck SH, et al. The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors. Eur J Pharmacol. 1987 Nov 24;144(1):109-11. DOI:10.1016/0014-2999(87)90017-3
[2] Raffa RB, et al. Scyliorhinin-I and -II induce reciprocal hindlimb scratching in mice: differentiation of spinal and supraspinal neurokinin receptors in vivo. Neurosci Lett. 1993 Aug 6;158(1):87-91. DOI:10.1016/0304-3940(93)90619-v

scyliorhinin II Preparation Products And Raw materials

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112748-19-3, scyliorhinin IIRelated Search:

Scyliorhinin I, Scy I: Shark Substance P Related Peptide SER-PRO-SER-ASN-SER-LYS-CYS-PRO-ASP-GLY-PRO-ASP-CYS-PHE-VAL-GLY-LEU-MET-NH2 H-ALA-LYS-PHE-ASP-LYS-PHE-TYR-GLY-LEU-MET-NH2

PubChem ID: 101569057

L-Methioninamide, L-seryl-L-prolyl-L-seryl-L-asparaginyl-L-seryl-L-lysyl-L-cysteinyl-L-prolyl-L-α-aspartylglycyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-valylglycyl-L-leucyl-, cyclic (7→13)-disulfide

112748-19-3

C77H119N21O26S3