5-formyl-2'-deoxyuridine

Product Name: 5-formyl-2'-deoxyuridine
CAS No.: 4494-26-2
Chemical Name: 5-formyl-2'-deoxyuridine
Synonyms: 5-Formyl-dU;5-formyl-2'-dU;α-Oxothymidine;Thymidine, α-oxo-;5-Formul-2’-deoxyuridine;2'-deoxy-5-forMyluridine;5-formyl-2'-deoxyuridine;1-(2-Deoxy-β-D-ribofuranosyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidine-5-carbaldehyde;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyriMidine-5-carbaldehyde
CBNumber: CB51358750
Molecular Formula: C10H12N2O6
Formula Weight: 256.21
MOL File: 4494-26-2.mol

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5-formyl-2'-deoxyuridine Property

Melting point:: 162 - 164°C
Density: 1.670±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly, Sonicated)
pka: 8.23±0.10(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: H953153
Product name: 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
Packaging: 25mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND29039
Product name: 2'-Deoxy-5-formyluridine
Packaging: 50mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND29039
Product name: 2'-Deoxy-5-formyluridine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND29039
Product name: 2'-Deoxy-5-formyluridine
Packaging: 25mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: ND29039
Product name: 2'-Deoxy-5-formyluridine
Packaging: 100mg
Price: $160
Updated: 2021/12/16

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5-formyl-2'-deoxyuridine Chemical Properties,Usage,Production

Uses

5-Formyl-2'-deoxyuridine is a product formed when the 5-methyl group of thymine in DNA undergoes oxidation due to exposure to gamma radiation or certain chemical agents. Serving as a biomarker of oxidative DNA damage, 5-formyl-2'-deoxyuridine is employed in investigations of DNA damage and repair mechanisms. Additionally, 5-Formyl-2'-deoxyuridine can be used in studies involving chemically crosslinking with peptides derived from the RecA protein[1].

References

[1] Sugiyama T, et al. Chemical cross-linking of peptides derived from RecA with single-stranded oligonucleotides containing 5-formyl-2′-deoxyuridine[J]. Nucleosides, Nucleotides and Nucleic Acids, 2001, 20(4-7): 1079-1083. DOI:10.1081/NCN-100002494

5-formyl-2'-deoxyuridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-formyl-2'-deoxyuridine Suppliers

China 49 India 2 United Kingdom 1 United States 4 Global 56

Hongene Biotech Corporation

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4494-26-2, 5-formyl-2'-deoxyuridineRelated Search:

5-formyl-2'-deoxyuridine 5-formyluridine

5-formyl-2'-deoxyuridine

1-(2-Deoxy-β-D-ribofuranosyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde

α-Oxothymidine

2'-deoxy-5-forMyluridine

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyriMidine-5-carbaldehyde

5-Formyl-dU

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidine-5-carbaldehyde

5-formyl-2'-dU

Thymidine, α-oxo-

5-Formul-2’-deoxyuridine

1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde - [H92421]

4494-26-2