glycyl-prolyl-glutamic acid
- Product Name
- glycyl-prolyl-glutamic acid
- CAS No.
- 32302-76-4
- Chemical Name
- glycyl-prolyl-glutamic acid
- Synonyms
- SC-252859;Glypromate;Gly-Pro-Glu >=98% (HPLC);glycyl-prolyl-glutamic acid;Glycyl-L-prolyl-L-glutamic acid;L-GlutaMic acid, glycyl-L-prolyl-;glycyl-prolyl-glutamic acid USP/EP/BP
- CBNumber
- CB51367862
- Molecular Formula
- C12H19N3O6
- Formula Weight
- 301.3
- MOL File
- 32302-76-4.mol
glycyl-prolyl-glutamic acid Property
- Boiling point:
- 675.7±55.0 °C(Predicted)
- Density
- 1.431±0.06 g/cm3(Predicted)
- storage temp.
- Store at 0°C
- solubility
- H2O: >5mg/mL
- form
- white powder
- pka
- 3.51±0.10(Predicted)
- color
- White to off-white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- G3923
- Product name
- Gly-Pro-Glu
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $91.3
- Updated
- 2024/03/01
- Product number
- G3923
- Product name
- Gly-Pro-Glu
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $381
- Updated
- 2024/03/01
- Product number
- PEP0004246
- Product name
- GLY-PRO-GLU
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $607.23
- Updated
- 2021/12/16
- Product number
- PEP0004246
- Product name
- GLY-PRO-GLU
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $795.56
- Updated
- 2021/12/16
glycyl-prolyl-glutamic acid Chemical Properties,Usage,Production
Definition
ChEBI: Gly-Pro-Glu is an oligopeptide.
Biological Activity
Gly-Pro-Glu (GPE) is a neuroactive peptide and prevents the binding of glutamate to N-methyl-D-aspartate (NMDA) receptor. It positively regulates the potassium-mediated release of acetylcholine from r at cortical slices. Thus, it is involved in the control of brain function. In vitro studies show th at this peptide confers neuroprotection to CA1-2 hippocampal neurons against excitotoxic insult.', 'Gly-Pro-Glu is a neuroprotective compound and the N-terminal tripeptide of IGF-1. Gly-Pro-Glu is neuroprotective after central administration in animal models of neurodegenerative processes, such as Huntington′s, Parkinson′s, Alzheimer′s diseases, and varies acute brain injury animal models. The neuroprotective activity is not related to its affinity to glutamate receptor. Findings indicate th at GPE mimics insulin-like growth factor I effects on the somatostatin system through a mechanism independent of β-amyloid clearance th at involves modulation of calcium and glycogen synthase kinase 3β signaling.
glycyl-prolyl-glutamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
glycyl-prolyl-glutamic acid Suppliers
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19881
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38631
- Advantage
- 58
- Tel
- --
- Fax
- --
- Country
- United States
- ProdList
- 6730
- Advantage
- 64
- Tel
- --
- Fax
- --
- Country
- United States
- ProdList
- 6773
- Advantage
- 87
- Tel
- --
- Fax
- --
- Country
- United States
- ProdList
- 5030
- Advantage
- 55